Cited 2 times in
A Planned Prospective, Randomized, Placebo-Controlled Multicenter Trial Assessing the Effect of Helicobacter pylori Eradication on the Healing of Iatrogenic Ulcer after Endoscopic Resection of Gastric Neoplasm.
DC Field | Value | Language |
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dc.contributor.author | 이용찬 | - |
dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2015-04-23T17:48:10Z | - |
dc.date.available | 2015-04-23T17:48:10Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103161 | - |
dc.description.abstract | BACKGROUND/AIMS: Helicobacter pylori eradication may facilitate the healing of iatrogenic ulcer after endoscopic resection of gastric neoplasm. This study involved designing a randomized, double-blinded, placebo-controlled, multicenter trial, performed by the Korean College of Helicobacter and Upper Gastrointestinal Research and the Medical Research Collaboration Center, Seoul National University Hospital. METHODS: We intend to enroll up to 232 patients H.-pylori-positive patients who have gastric adenoma or early gastric cancer after endoscopic resection. The enrolled patients are being randomly allocated to the H.-pylori-eradication-plus-proton-pump-inhibitor group or the placebo-plus-proton-pump-inhibitor group based on their histology results and the size of the resected specimen. After random allocation, the iatrogenic ulcer size and stage are evaluated at 4- and 8-week follow-ups (with a window of ±7 days). The primary end point is the healing rate of the ulcer by stage, and the secondary end point is the rate of ulcer size reduction, relief rate from ulcer-related symptoms, and adverse-event rates. RESULTS: More than 90% of the target subjects have already been enrolled into the study and are receiving ongoing periodic monitoring by the Medical Research Collaboration Center. CONCLUSIONS: Completion of the study should reveal whether H. pylori eradication can facilitate the healing of ulcer after endoscopic resection in Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 514~517 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | A Planned Prospective, Randomized, Placebo-Controlled Multicenter Trial Assessing the Effect of Helicobacter pylori Eradication on the Healing of Iatrogenic Ulcer after Endoscopic Resection of Gastric Neoplasm. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Sang Gyun Kim | - |
dc.contributor.googleauthor | Ho June Song | - |
dc.contributor.googleauthor | Il Ju Choi | - |
dc.contributor.googleauthor | Joo Young Cho | - |
dc.contributor.googleauthor | Hwoon-Yong Jung | - |
dc.contributor.googleauthor | Bora Keum | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.contributor.googleauthor | Jae Gyu Kim | - |
dc.contributor.googleauthor | Sue K. Park | - |
dc.contributor.googleauthor | Byung Joo Park | - |
dc.contributor.googleauthor | Hyun Chae Jung | - |
dc.identifier.doi | 10.5009/gnl.2010.4.4.514 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 21253301 | - |
dc.subject.keyword | Endoscopic resection | - |
dc.subject.keyword | Eradication | - |
dc.subject.keyword | Helicobacter pylori | - |
dc.subject.keyword | Iatrogenic ulcer | - |
dc.subject.keyword | Medical Research Collaboration Center | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Cheon, Jae Hee | - |
dc.citation.volume | 4 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 514 | - |
dc.citation.endPage | 517 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.4(4) : 514-517, 2010 | - |
dc.identifier.rimsid | 35733 | - |
dc.type.rims | ART | - |
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