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Triiodothyronine level predicts visceral obesity and atherosclerosis in euthyroid, overweight and obese subjects: T3 and visceral obesity

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dc.contributor.author김경래-
dc.contributor.author남지선-
dc.contributor.author박종숙-
dc.contributor.author안철우-
dc.contributor.author이은직-
dc.contributor.author이현철-
dc.contributor.author조민호-
dc.contributor.author차봉수-
dc.date.accessioned2015-04-23T17:47:06Z-
dc.date.available2015-04-23T17:47:06Z-
dc.date.issued2010-
dc.identifier.issn1871-403X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/103126-
dc.description.abstractSummary: Objective: We assessed how thyroid hormones affect the visceral obesity and atherosclerosis in euthyroid, overweight and obese Asian subjects.Methods: Metabolic parameters and thyroid hormone levels were measured in 177 subjects who visited obesity clinic at Gangnam Severance Hospital. Total adipose tissue area (TAT), subcutaneous adipose tissue area (SAT), visceral adipose tissue area (VAT) were quantified by computerized tomography scan, and, pulse wave velocity (PWV) was measured as a marker of atherosclerosis.Results: T3 was significantly related to all the measures of abdominal fat, TAT (P = 0.001), SAT (P = 0.015), VAT (P < 0.001), and waist circumference (P = 0.001) as well as BMI (P = 0.017) and total body fat percent (P = 0.001) after adjusting for age and sex. In multiple regression analysis, T3 was independently associated with VAT (β = 0.486, P = 0.009). There was a positive correlation between T3 and PWV.Conclusions: T3 level is positively associated with the amount of visceral fat and PWV. Visceral obesity seems to cause an increase in circulating T3 level as an adaptational response to increase the energy expenditure, and thus a more close attention and an effort to assess cardiovascular risks should be made to people with high normal T3 level-
dc.description.statementOfResponsibilityopen-
dc.format.extente247-342-
dc.relation.isPartOfOBESITY RESEARCH & CLINICAL PRACTICE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleTriiodothyronine level predicts visceral obesity and atherosclerosis in euthyroid, overweight and obese subjects: T3 and visceral obesity-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJi Sun Nam-
dc.contributor.googleauthorMinho Cho-
dc.contributor.googleauthorJong Suk Park-
dc.contributor.googleauthorChul Woo Ahn-
dc.contributor.googleauthorBong Soo Cha-
dc.contributor.googleauthorEun Jig Lee-
dc.contributor.googleauthorSung Kil Lim-
dc.contributor.googleauthorKyung Rae Kim-
dc.contributor.googleauthorHyun Chul Lee-
dc.identifier.doi10.1016/j.orcp.2010.08.003-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00294-
dc.contributor.localIdA01268-
dc.contributor.localIdA02270-
dc.contributor.localIdA03050-
dc.contributor.localIdA03301-
dc.contributor.localIdA03819-
dc.contributor.localIdA03996-
dc.contributor.localIdA01660-
dc.relation.journalcodeJ02406-
dc.identifier.pmid24345698-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1871403X10000207-
dc.subject.keywordThyroid hormone-
dc.subject.keywordVisceral obesity-
dc.subject.keywordFat CT-
dc.subject.keywordPulse wave velocity-
dc.subject.keywordAtherosclerosis-
dc.contributor.alternativeNameKim, Kyung Rae-
dc.contributor.alternativeNameNam, Ji Sun-
dc.contributor.alternativeNamePark, Jong Suk-
dc.contributor.alternativeNameAhn, Chul Woo-
dc.contributor.alternativeNameLee, Eun Jig-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameCho, Min Ho-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.affiliatedAuthorKim, Kyung Rae-
dc.contributor.affiliatedAuthorNam, Ji Sun-
dc.contributor.affiliatedAuthorAhn, Chul Woo-
dc.contributor.affiliatedAuthorLee, Eun Jig-
dc.contributor.affiliatedAuthorLee, Hyun Chul-
dc.contributor.affiliatedAuthorCho, Min Ho-
dc.contributor.affiliatedAuthorCha, Bong Soo-
dc.contributor.affiliatedAuthorPark, Jong Suk-
dc.citation.volume4-
dc.citation.number4-
dc.citation.startPage247-
dc.citation.endPage342-
dc.identifier.bibliographicCitationOBESITY RESEARCH & CLINICAL PRACTICE, Vol.4(4) : 247-342, 2010-
dc.identifier.rimsid35706-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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