Cited 33 times in
Reduced visual P300 amplitudes in individuals at ultra-high risk for psychosis and first-episode schizophrenia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남궁기 | - |
dc.contributor.author | 송동호 | - |
dc.contributor.author | 안석균 | - |
dc.date.accessioned | 2015-04-23T17:45:33Z | - |
dc.date.available | 2015-04-23T17:45:33Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0304-3940 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103076 | - |
dc.description.abstract | The purpose of this study was to investigate whether individuals at ultra-high risk (UHR) for psychosis and patients experiencing first-episode schizophrenia had impairments in visual information processing as indexed by the visual P300 event-related potential. Sixteen UHR individuals, 21 first-episode schizophrenia patients, and 16 healthy controls were included. Participants were asked to perform a visuospatial oddball task while undergoing an electroencephalogram. The UHR and first-episode groups showed reduced P300 amplitudes in comparison to healthy controls. P300 amplitudes were negatively correlated with severity of negative symptoms in both the UHR and first-episode groups. These results suggest that the visual P300 may be a neurobiological vulnerability marker, reflecting neurophysiological abnormalities associated with enduring negative symptoms in schizophrenia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 156~160 | - |
dc.relation.isPartOf | NEUROSCIENCE LETTERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Brain Mapping/methods | - |
dc.subject.MESH | Disease Susceptibility | - |
dc.subject.MESH | Early Diagnosis | - |
dc.subject.MESH | Electroencephalography/methods | - |
dc.subject.MESH | Event-Related Potentials,P300/physiology* | - |
dc.subject.MESH | Evoked Potentials,Visual/physiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neuropsychological Tests/standards | - |
dc.subject.MESH | Photic Stimulation/methods | - |
dc.subject.MESH | Psychotic Disorders/diagnosis* | - |
dc.subject.MESH | Psychotic Disorders/physiopathology* | - |
dc.subject.MESH | RiskAssessment/methods | - |
dc.subject.MESH | RiskFactors | - |
dc.subject.MESH | Schizophrenia/diagnosis* | - |
dc.subject.MESH | Schizophrenia/physiopathology* | - |
dc.subject.MESH | VisualCortex/physiopathology* | - |
dc.subject.MESH | VisualPathways/physiopathology | - |
dc.subject.MESH | Young Adult | - |
dc.title | Reduced visual P300 amplitudes in individuals at ultra-high risk for psychosis and first-episode schizophrenia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | Su Young Lee | - |
dc.contributor.googleauthor | Kee Namkoong | - |
dc.contributor.googleauthor | Hye Hyun Cho | - |
dc.contributor.googleauthor | Dong-Ho Song | - |
dc.contributor.googleauthor | Suk Kyoon An | - |
dc.identifier.doi | 10.1016/j.neulet.2010.09.035 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01240 | - |
dc.contributor.localId | A02018 | - |
dc.contributor.localId | A02227 | - |
dc.relation.journalcode | J02364 | - |
dc.identifier.eissn | 1872-7972 | - |
dc.identifier.pmid | 20858531 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0304394010012528 | - |
dc.subject.keyword | Ultra-high risk for psychosisFirst-episode schizophreniaP300Event-related potentialsNegative symptomsVisuospatial oddball task | - |
dc.contributor.alternativeName | Namkoong, Kee | - |
dc.contributor.alternativeName | Song, Dong Ho | - |
dc.contributor.alternativeName | An, Suk Kyoon | - |
dc.contributor.affiliatedAuthor | Namkoong, Kee | - |
dc.contributor.affiliatedAuthor | Song, Dong Ho | - |
dc.contributor.affiliatedAuthor | An, Suk Kyoon | - |
dc.citation.volume | 486 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 156 | - |
dc.citation.endPage | 160 | - |
dc.identifier.bibliographicCitation | NEUROSCIENCE LETTERS, Vol.486(3) : 156-160, 2010 | - |
dc.identifier.rimsid | 35668 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.