Cited 10 times in
Efficacy of Tandem High-Dose Chemotherapy and Autologous Stem Cell Rescue in Patients Over 1 Year of Age with Stage 4 Neuroblastoma: The Korean Society of Pediatric Hematology-Oncology Experience Over 6 Years (2000-2005).
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 원성철 | - |
dc.contributor.author | 유철주 | - |
dc.date.accessioned | 2015-04-23T17:45:04Z | - |
dc.date.available | 2015-04-23T17:45:04Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103060 | - |
dc.description.abstract | The efficacy of tandem high-dose chemotherapy and autologous stem cell rescue (HDCT/ASCR) was investigated in patients with high-risk neuroblastoma. Patients over 1 yr of age who were newly diagnosed with stage 4 neuroblastoma from January 2000 to December 2005 were enrolled in The Korean Society of Pediatric Hematology-Oncology registry. All patients who were assigned to receive HDCT/ASCR at diagnosis were retrospectively analyzed to investigate the efficacy of single or tandem HDCT/ASCR. Seventy and 71 patients were assigned to receive single or tandem HDCT/ASCR at diagnosis. Fifty-seven and 59 patients in the single or tandem HDCT group underwent single or tandem HDCT/ASCR as scheduled. Twenty-four and 38 patients in the single or tandem HDCT group remained event free with a median follow-up of 56 (24-88) months. When the survival rate was analyzed according to intent-to-treat at diagnosis, the probability of the 5-yr event-free survival+/-95% confidence intervals was higher in the tandem HDCT group than in the single HDCT group (51.2+/-12.4% vs. 31.3+/-11.5%, P=0.030). The results of the present study demonstrate that the tandem HDCT/ASCR strategy is significantly better than the single HDCT/ASCR strategy for improved survival in the treatment of high-risk neuroblastoma patients | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 691~697 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Combined Modality Therapy/mortality | - |
dc.subject.MESH | Drug Therapy/mortality* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Longitudinal Studies | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neuroblastoma/mortality* | - |
dc.subject.MESH | Neuroblastoma/therapy* | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Risk Assessment/methods | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | StemCellTransplantation/mortality* | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Efficacy of Tandem High-Dose Chemotherapy and Autologous Stem Cell Rescue in Patients Over 1 Year of Age with Stage 4 Neuroblastoma: The Korean Society of Pediatric Hematology-Oncology Experience Over 6 Years (2000-2005). | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Ki Woong Sung | - |
dc.contributor.googleauthor | Hyo Seop Ahn | - |
dc.contributor.googleauthor | Bin Cho | - |
dc.contributor.googleauthor | Yong-Mook Choi | - |
dc.contributor.googleauthor | Nack Gyun Chung | - |
dc.contributor.googleauthor | Tai Ju Hwang | - |
dc.contributor.googleauthor | Ho Joon Im | - |
dc.contributor.googleauthor | Dae Chul Jeong | - |
dc.contributor.googleauthor | Hyoung Jin Kang | - |
dc.contributor.googleauthor | Hong Hoe Koo | - |
dc.contributor.googleauthor | Hoon Kook | - |
dc.contributor.googleauthor | Hack Ki Kim | - |
dc.contributor.googleauthor | Chuhl Joo Lyu | - |
dc.contributor.googleauthor | Jong Jin Seo | - |
dc.contributor.googleauthor | Hee Young Shin | - |
dc.contributor.googleauthor | Keon Hee Yoo | - |
dc.contributor.googleauthor | Sung Chul Won | - |
dc.contributor.googleauthor | Kun Soo Lee | - |
dc.identifier.doi | 10.3346/jkms.2010.25.5.691 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02434 | - |
dc.contributor.localId | A02524 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 20436703 | - |
dc.subject.keyword | Neuroblastoma | - |
dc.subject.keyword | High-dose Chemotherapy | - |
dc.subject.keyword | Transplantation | - |
dc.subject.keyword | Autologous | - |
dc.contributor.alternativeName | Won, Sung Chul | - |
dc.contributor.alternativeName | Lyu, Chuhl Joo | - |
dc.contributor.affiliatedAuthor | Won, Sung Chul | - |
dc.contributor.affiliatedAuthor | Lyu, Chuhl Joo | - |
dc.citation.volume | 25 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 691 | - |
dc.citation.endPage | 697 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.25(5) : 691-697, 2010 | - |
dc.identifier.rimsid | 35656 | - |
dc.type.rims | ART | - |
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