Cited 64 times in
Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience
DC Field | Value | Language |
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dc.contributor.author | 김유진 | - |
dc.contributor.author | 박준철 | - |
dc.contributor.author | 서주희 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 정현수 | - |
dc.date.accessioned | 2015-04-23T17:40:57Z | - |
dc.date.available | 2015-04-23T17:40:57Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0930-2794 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102928 | - |
dc.description.abstract | BACKGROUND: Endoscopic resection is widely accepted as the primary treatment for early gastric cancer (EGC) without lymph node metastasis. A new and refined technique, endoscopic submucosal dissection (ESD), may prove to be more effective; however, incomplete resection and local recurrence present ongoing concerns. We sought to determine the clinicopathological features associated with local recurrence in patients with EGC following endoscopic resection. METHODS: We enrolled in this study 239 EGC patients treated by endoscopic resection between January 2002 and January 2008. RESULTS: Fifty EGC lesions were treated by conventional endoscopic mucosal resection (EMR group) and 189 EGC lesions were treated by ESD (ESD group). During the follow-up period (mean = 30.3 months), the rates for en bloc resection and complete resection (defined as en bloc resection with negative resection margin) were 64% (32/50) and 60% (30/50), respectively, in the EMR group, and 86.8% (164/189) and 79.9% (151/189), respectively, in the ESD group. We observed seven local recurrences in the ESD group, though only one with complete resection by ESD had a local recurrence. The EMR group showed a significantly higher recurrence rate than did the ESD group (18% vs. 3.7%, respectively, p < 0.001). Incomplete resection significantly increased local recurrence risk, and larger tumor size and use of EMR increased the risk for incomplete resection. Most lesions (3/4) treated with additional argon plasma coagulation for an initial recurrence had recurred again. CONCLUSIONS: Despite the potential advantages in treating EGC with ESD, a risk for local recurrence remains. All patients treated with EMR, even with curative resection, and those with incomplete resection after ESD require conscientious surveillance for local recurrence. Furthermore, a large prospective study will be required to determine the best treatment modality for local recurrence | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2842~2849 | - |
dc.relation.isPartOf | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Endoscopy, Gastrointestinal* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gastric Mucosa/pathology | - |
dc.subject.MESH | Gastric Mucosa/surgery | - |
dc.subject.MESH | Gastroscopy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local*/pathology | - |
dc.subject.MESH | Neoplasm Recurrence, Local*/surgery | - |
dc.subject.MESH | Stomach Neoplasms/pathology | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.title | Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Ju Hee Seo | - |
dc.contributor.googleauthor | Yu Jin Kim | - |
dc.contributor.googleauthor | Hyunsoo Chung | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.identifier.doi | 10.1007/s00464-010-1060-8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A01909 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A00787 | - |
dc.relation.journalcode | J02703 | - |
dc.identifier.eissn | 1432-2218 | - |
dc.identifier.pmid | 20428894 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00464-010-1060-8 | - |
dc.contributor.alternativeName | Kim, Yoo Jin | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Seo, Ju Hee | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Chung, Hyun Soo | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Seo, Ju Hee | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Kim, Yoo Jin | - |
dc.citation.volume | 24 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2842 | - |
dc.citation.endPage | 2849 | - |
dc.identifier.bibliographicCitation | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol.24(11) : 2842-2849, 2010 | - |
dc.identifier.rimsid | 35099 | - |
dc.type.rims | ART | - |
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