3 536

Cited 64 times in

Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience

DC Field Value Language
dc.contributor.author김유진-
dc.contributor.author박준철-
dc.contributor.author서주희-
dc.contributor.author신성관-
dc.contributor.author이상길-
dc.contributor.author이용찬-
dc.contributor.author정현수-
dc.date.accessioned2015-04-23T17:40:57Z-
dc.date.available2015-04-23T17:40:57Z-
dc.date.issued2010-
dc.identifier.issn0930-2794-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/102928-
dc.description.abstractBACKGROUND: Endoscopic resection is widely accepted as the primary treatment for early gastric cancer (EGC) without lymph node metastasis. A new and refined technique, endoscopic submucosal dissection (ESD), may prove to be more effective; however, incomplete resection and local recurrence present ongoing concerns. We sought to determine the clinicopathological features associated with local recurrence in patients with EGC following endoscopic resection. METHODS: We enrolled in this study 239 EGC patients treated by endoscopic resection between January 2002 and January 2008. RESULTS: Fifty EGC lesions were treated by conventional endoscopic mucosal resection (EMR group) and 189 EGC lesions were treated by ESD (ESD group). During the follow-up period (mean = 30.3 months), the rates for en bloc resection and complete resection (defined as en bloc resection with negative resection margin) were 64% (32/50) and 60% (30/50), respectively, in the EMR group, and 86.8% (164/189) and 79.9% (151/189), respectively, in the ESD group. We observed seven local recurrences in the ESD group, though only one with complete resection by ESD had a local recurrence. The EMR group showed a significantly higher recurrence rate than did the ESD group (18% vs. 3.7%, respectively, p < 0.001). Incomplete resection significantly increased local recurrence risk, and larger tumor size and use of EMR increased the risk for incomplete resection. Most lesions (3/4) treated with additional argon plasma coagulation for an initial recurrence had recurred again. CONCLUSIONS: Despite the potential advantages in treating EGC with ESD, a risk for local recurrence remains. All patients treated with EMR, even with curative resection, and those with incomplete resection after ESD require conscientious surveillance for local recurrence. Furthermore, a large prospective study will be required to determine the best treatment modality for local recurrence-
dc.description.statementOfResponsibilityopen-
dc.format.extent2842~2849-
dc.relation.isPartOfSURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHEndoscopy, Gastrointestinal*-
dc.subject.MESHFemale-
dc.subject.MESHGastric Mucosa/pathology-
dc.subject.MESHGastric Mucosa/surgery-
dc.subject.MESHGastroscopy-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Recurrence, Local*/pathology-
dc.subject.MESHNeoplasm Recurrence, Local*/surgery-
dc.subject.MESHStomach Neoplasms/pathology-
dc.subject.MESHStomach Neoplasms/surgery*-
dc.titlePredictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJun Chul Park-
dc.contributor.googleauthorSang Kil Lee-
dc.contributor.googleauthorJu Hee Seo-
dc.contributor.googleauthorYu Jin Kim-
dc.contributor.googleauthorHyunsoo Chung-
dc.contributor.googleauthorSung Kwan Shin-
dc.contributor.googleauthorYong Chan Lee-
dc.identifier.doi10.1007/s00464-010-1060-8-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01676-
dc.contributor.localIdA01909-
dc.contributor.localIdA02112-
dc.contributor.localIdA02812-
dc.contributor.localIdA02988-
dc.contributor.localIdA00787-
dc.relation.journalcodeJ02703-
dc.identifier.eissn1432-2218-
dc.identifier.pmid20428894-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00464-010-1060-8-
dc.contributor.alternativeNameKim, Yoo Jin-
dc.contributor.alternativeNamePark, Jun Chul-
dc.contributor.alternativeNameSeo, Ju Hee-
dc.contributor.alternativeNameShin, Sung Kwan-
dc.contributor.alternativeNameLee, Sang Kil-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.alternativeNameChung, Hyun Soo-
dc.contributor.affiliatedAuthorPark, Jun Chul-
dc.contributor.affiliatedAuthorSeo, Ju Hee-
dc.contributor.affiliatedAuthorShin, Sung Kwan-
dc.contributor.affiliatedAuthorLee, Sang Kil-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.contributor.affiliatedAuthorKim, Yoo Jin-
dc.citation.volume24-
dc.citation.number11-
dc.citation.startPage2842-
dc.citation.endPage2849-
dc.identifier.bibliographicCitationSURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol.24(11) : 2842-2849, 2010-
dc.identifier.rimsid35099-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.