Cited 54 times in
Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study.
DC Field | Value | Language |
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dc.contributor.author | 김효송 | - |
dc.date.accessioned | 2015-04-23T17:39:13Z | - |
dc.date.available | 2015-04-23T17:39:13Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102873 | - |
dc.description.abstract | BACKGROUND: We performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection. METHODS: Of the 141 patients who were diagnosed of non-cutaneous melanoma at 4 institutions in Korea between June 1992 and May 2005, 129 (91.5%) satisfied the selection criteria. RESULTS: Of the 129 noncutaneous melanoma patients, 14 patients had ocular melanoma and 115 patients had mucosal melanoma. For mucosal melanoma, anorectum was the most common anatomic site (n=39, 30.2%) which was followed by nasal cavity (n=30, 23.3%), genitourinary (n=21, 16.3%), oral cavity (n=14, 10.9%), upper gastrointestinal tract (n=6, 4.7%) and maxillary sinus (n=5, 3.9%) in the order of frequency. With the median 64.5 (range 4.3-213.0) months follow-up, the median overall survival were 24.4 months (95% CI 13.2-35.5) for all patients, and 34.6 (95% CI 24.5-44.7) months for curatively resected mucosal melanoma patients. Adverse prognostic factors of survival for 87 curatively resected mucosal melanoma patients were complete resection (R1 resection margin), and age>50 years. For 14 ocular melanoma, Survival outcome was much better than mucosal melanoma with 73.3% of 2 year OS and 51.2 months of median OS (P=.04). CONCLUSION: Prognosis differed according to primary sites of noncutaneous melanoma. Based on our study, noncutaneous melanoma patients should be treated differently to improve survival outcome. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 167 | - |
dc.relation.isPartOf | BMC CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma/mortality | - |
dc.subject.MESH | Carcinoma/pathology | - |
dc.subject.MESH | Carcinoma/surgery* | - |
dc.subject.MESH | Chemotherapy, Adjuvant | - |
dc.subject.MESH | Eye Neoplasms/mortality | - |
dc.subject.MESH | Eye Neoplasms/pathology | - |
dc.subject.MESH | Eye Neoplasms/surgery* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Melanoma/mortality | - |
dc.subject.MESH | Melanoma/pathology | - |
dc.subject.MESH | Melanoma/surgery* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Mucous Membrane/pathology | - |
dc.subject.MESH | Mucous Membrane/surgery | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Radiotherapy, Adjuvant | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hyo Song Kim | - |
dc.contributor.googleauthor | Eun Kyoung Kim | - |
dc.contributor.googleauthor | Hyun Jung Jun | - |
dc.contributor.googleauthor | Sung Yong Oh | - |
dc.contributor.googleauthor | Keon Woo Park | - |
dc.contributor.googleauthor | Do Hyoung Lim | - |
dc.contributor.googleauthor | Soon Il Lee | - |
dc.contributor.googleauthor | Jung Han Kim | - |
dc.contributor.googleauthor | Kyoung Mee Kim | - |
dc.contributor.googleauthor | Dae Ho Lee | - |
dc.contributor.googleauthor | Jeeyun Lee | - |
dc.identifier.doi | 10.1186/1471-2407-10-167 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01202 | - |
dc.relation.journalcode | J00351 | - |
dc.identifier.eissn | 1471-2407 | - |
dc.identifier.pmid | 20426858 | - |
dc.subject.keyword | Melanoma | - |
dc.subject.keyword | Overall Survival | - |
dc.subject.keyword | Median Overall Survival | - |
dc.subject.keyword | Melanoma Patient | - |
dc.subject.keyword | Cutaneous Melanoma | - |
dc.contributor.alternativeName | Kim, Hyo Song | - |
dc.contributor.affiliatedAuthor | Kim, Hyo Song | - |
dc.citation.volume | 10 | - |
dc.citation.startPage | 167 | - |
dc.identifier.bibliographicCitation | BMC CANCER, Vol.10 : 167, 2010 | - |
dc.identifier.rimsid | 35061 | - |
dc.type.rims | ART | - |
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