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골육종으로 진행된 개화성 골 이형성증의 증례보고

Other Titles
 A Case Report of Osteogenic Sarcoma Arising from Florid Osseous Dysplasia 
 김현실  ;  김남희  ;  육종인  ;  김진  ;  박혁  ;  차인호 
 Korean Journal of Oral and Maxillofacial Pathology, Vol.34(6) : 383-386, 2010 
Journal Title
Korean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지)
Issue Date
Florid osseous dysplasia ; Osteogenic sarcoma ; Premalignant lesion ; Fibro-osseous lesion
Osteogenic sarcoma is primary malignant bone tumor. It can arise de novo or from the benign precursors lesions, like Paget’s disease, giant cell tumor, chronic osteomyelitis, osteoblastoma, and fibrous dysplasia. Here, we present a case of osteogenic sarcoma arising from florid osseous dysplasia appearing as a rapidly growing bony bulging mass in 44-year-old Korean female who had at first been non-symptomatic, but later suffered from the numbness of chin and lower lip. The radiologic images revealed the mixed radiopaque- radiolucent intraosseous lesions throughout the mandible, which were diagnosed as florid osseous dysplasia pathologically. But only after 6 months, the lesions were substituted by the radiological ill-defined diffuse bony sclerotic lesion with bone destruction, accompanying the interrupted periosteal bone formation, which were pathologically diagnosed as osteogenic sarcomas. These serial clinicopathologic changes imply the malignant progression of florid osseous dysplasia rather than the collision of benign condition, florid osseous dysplasia
and malignant tumor, osteogenic sarcoma. The possibility for fibro-osseous lesion of the jaw as premalignant lesion should not be overlooked; therefore, periodic check-ups for the lesions are necessary. Proper evaluation and interpretation for clinical neural symptom and radiologic change of bone density may lead to the correct differential diagnosis and therapeutic intervention.
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Appears in Collections:
2. College of Dentistry (치과대학) > Research Institute (부설연구소) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Radiology (영상치의학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Hee(김남희) ORCID logo https://orcid.org/0000-0002-3087-5276
Kim, Jin(김진)
Kim, Hyun Sil(김현실) ORCID logo https://orcid.org/0000-0003-3614-1764
Park, Hyuk(박혁)
Yook, Jong In(육종인) ORCID logo https://orcid.org/0000-0002-7318-6112
Cha, In Ho(차인호) ORCID logo https://orcid.org/0000-0001-8259-2190
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