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Inhibitory Effects of Neo Muscat Grape Vine Extracts on Melanin Biosynthesis

Authors
 Sang Yoon Choi  ;  Yeon Hee Kong  ;  Yeonmi Lee  ;  Ji Hwoon Baek  ;  Seung Hun Lee  ;  Pyeongjae Lee 
Citation
 Journal of Applied Biological Chemistry, Vol.53(5) : 566-569, 2010 
Journal Title
 Journal of Applied Biological Chemistry 
ISSN
 1738-2203 
Issue Date
2010
Keywords
depigmenting agent ; grape vine ; melanin ; tyrosinase
Abstract
Neo Muscat grape vine extracts significantly inhibited melanin production in melanocyte stimulating hormone-stimulated B16 cells. They also exhibited tyrosinase inhibitory activity and reduced the levels of intra-cellular tyrosinase. Moreover, when the extracts were treated with UV B-induced hyper-pigmented brown guinea pig skin, depigmenting activity was observed, but with no visible edema. These results indicate that the vine extracts of Neo Muscat grapes might prove useful as a skin depigmenting agent
Files in This Item:
T201003997.pdf Download
DOI
10.3839/jksabc.2010.087
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Seung Hun(이승헌)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102570
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