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양극성장애와 Catechol O-Methyltransferase 및 Monoamine Oxidase A 유전자 다형성의 연관성
DC Field | Value | Language |
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dc.contributor.author | 김세주 | - |
dc.contributor.author | 김승준 | - |
dc.contributor.author | 석정호 | - |
dc.contributor.author | 송동호 | - |
dc.contributor.author | 이은 | - |
dc.contributor.author | 조현상 | - |
dc.date.accessioned | 2015-04-23T17:29:01Z | - |
dc.date.available | 2015-04-23T17:29:01Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1738-0960 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102550 | - |
dc.description.abstract | involved in metabolizing the monoamine, are associated with the onset of bipolar disorder or the clinical variables such as suicide attempt during illness, age of onset and family history. This study investigated the genotype or allele frequency of COMT and MAOA genes in bipolar disorder patients and compared the results to those of healthy controls. Method:We collected the blood of 184 bipolar patients and 216 healthy controls. COMT Val158Met and MAOA EcoRV/C1460T were genotyped. T-test, analysis of variance, chi-square test and Fisher’s exact test were used. Results:There was no significant association between COMT Val158Met and MAOA EcoRV/C1460T and onset of bipolar disorder. In the bipolar patients group, there was no significant association between COMT Val158Met and MAOA EcoRV/C1460T and clinical variables such as suicidal attempt during illness, family history and age of onset. Conclusion:The present findings indicate that there is no association between COMT Val158Met and MAOA EcoRV/C1460T and onset of bipolar disorder or clinical variables such as suicidal attempt during illness, age of onset and family history. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | Journal of Korean Society for Depressive and Bipolar Disorders (우울ㆍ조울병) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 양극성장애와 Catechol O-Methyltransferase 및 Monoamine Oxidase A 유전자 다형성의 연관성 | - |
dc.title.alternative | Associatin Between Catechol O-Methyltransferase Gene, Monoamine Ocidase A Gene and Bipolar Disorder | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | 김승준 | - |
dc.contributor.googleauthor | 조현상 | - |
dc.contributor.googleauthor | 김세주 | - |
dc.contributor.googleauthor | 전덕인 | - |
dc.contributor.googleauthor | 이은 | - |
dc.contributor.googleauthor | 석정호 | - |
dc.contributor.googleauthor | 송동호 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00660 | - |
dc.contributor.localId | A00604 | - |
dc.contributor.localId | A01929 | - |
dc.contributor.localId | A02018 | - |
dc.contributor.localId | A03032 | - |
dc.contributor.localId | A03928 | - |
dc.relation.journalcode | J01534 | - |
dc.contributor.alternativeName | Kim, Se Joo | - |
dc.contributor.alternativeName | Kim, Seung Jun | - |
dc.contributor.alternativeName | Seok, Jeong Ho | - |
dc.contributor.alternativeName | Song, Dong Ho | - |
dc.contributor.alternativeName | Lee, Eun | - |
dc.contributor.alternativeName | Cho, Hyun Sang | - |
dc.contributor.affiliatedAuthor | Kim, Seung Jun | - |
dc.contributor.affiliatedAuthor | Kim, Se Joo | - |
dc.contributor.affiliatedAuthor | Seok, Jeong Ho | - |
dc.contributor.affiliatedAuthor | Song, Dong Ho | - |
dc.contributor.affiliatedAuthor | Lee, Eun | - |
dc.contributor.affiliatedAuthor | Cho, Hyun Sang | - |
dc.citation.volume | 8 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 24 | - |
dc.citation.endPage | 30 | - |
dc.identifier.bibliographicCitation | Journal of Korean Society for Depressive and Bipolar Disorders (우울ㆍ조울병), Vol.8(1) : 24-30, 2010 | - |
dc.identifier.rimsid | 49827 | - |
dc.type.rims | ART | - |
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