Cited 14 times in
Skin disorders in Korean patients infected with human immunodeficiency virus and their association with a CD4 lymphocyte count: a preliminary study
DC Field | Value | Language |
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dc.contributor.author | 오상호 | - |
dc.contributor.author | 이광훈 | - |
dc.date.accessioned | 2015-04-23T17:27:25Z | - |
dc.date.available | 2015-04-23T17:27:25Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0926-9959 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102500 | - |
dc.description.abstract | BACKGROUND: Dermatological disorders are quite common in human immunodeficiency virus (HIV)-infected patients. However, cutaneous findings in Korean HIV-infected patients have not been properly investigated. OBJECTIVE: To investigate the spectrum of dermatological disorders in Korean HIV-infected individuals according to a CD4 lymphocyte count. METHODS: A retrospective clinical study was carried out from June 2002 to January 2008. We comprehensively collected information regarding HIV-associated skin problems, laboratory data and the history of highly active antiretroviral therapy (HAART). RESULTS: Ninety-nine HIV-seropositive patients (mean age: 39.6 ± 11.3 years, males: 94.9%) were included in this study. Of them, 55 patients (55.6%) presented with at least one skin problem. The four most common dermatological disorders were eosinophilic pustular folliculitis (18.6%), symptomatic syphilis (comprising of primary and secondary syphilis) (17.1%), seborrhoeic dermatitis (17.1%) and condyloma acuminatum (12.8%). The group with a CD4 lymphocyte count < 200 · 10⁶ cells ⁄ L showed a significantly higher prevalence of Kaposi sarcoma compared with the group with a CD4 lymphocyte count > 200 · 10⁶ cells ⁄ L (P = 0.014). Condyloma was more prevalent in the group with a CD4 count > 200 · 10⁶ cells ⁄ L (P = 0.022). The patients treated with HAART had a lower prevalence of neurosyphilis compared with the non-treated group (P = 0.018). CONCLUSIONS: Diverse dermatological conditions were demonstrated in Korean HIV-infected patients. Kaposi sarcoma was associated with a low CD4 lymphocyte count, but condyloma was associated with a high CD4 lymphocyte count. The prevalence of syphilis in our study was higher than that of Western countries. HAART seemed to be associated with the low prevalence of neurosyphilis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1476~1480 | - |
dc.relation.isPartOf | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Antiretroviral Therapy, Highly Active | - |
dc.subject.MESH | CD4 Lymphocyte Count* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | HIV Infections/complications* | - |
dc.subject.MESH | HIV Infections/drug therapy | - |
dc.subject.MESH | HIV Infections/immunology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Skin Diseases/complications* | - |
dc.subject.MESH | Skin Diseases/immunology | - |
dc.title | Skin disorders in Korean patients infected with human immunodeficiency virus and their association with a CD4 lymphocyte count: a preliminary study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학) | - |
dc.contributor.googleauthor | T-G Kim | - |
dc.contributor.googleauthor | K-H Lee | - |
dc.contributor.googleauthor | S-H Oh | - |
dc.identifier.doi | 10.1111/j.1468-3083.2010.03675.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02370 | - |
dc.contributor.localId | A02674 | - |
dc.relation.journalcode | J01783 | - |
dc.identifier.eissn | 1468-3083 | - |
dc.identifier.pmid | 20384683 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1468-3083.2010.03675.x/abstract | - |
dc.subject.keyword | CD4 lymphocyte counts | - |
dc.subject.keyword | human immunodeficiency virus infection | - |
dc.subject.keyword | skin diseases | - |
dc.contributor.alternativeName | Oh, Sang Ho | - |
dc.contributor.alternativeName | Lee, Kwang Hoon | - |
dc.contributor.affiliatedAuthor | Oh, Sang Ho | - |
dc.contributor.affiliatedAuthor | Lee, Kwang Hoon | - |
dc.citation.volume | 24 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1476 | - |
dc.citation.endPage | 1480 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, Vol.24(12) : 1476-1480, 2010 | - |
dc.identifier.rimsid | 49797 | - |
dc.type.rims | ART | - |
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