Cited 41 times in
Prevalence and diversity of carbapenemases among imipenem-nonsusceptible Acinetobacter isolates in Korea: emergence of a novel OXA-182.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김창기 | - |
dc.contributor.author | 이경원 | - |
dc.contributor.author | 이양순 | - |
dc.contributor.author | 이혁민 | - |
dc.contributor.author | 정석훈 | - |
dc.contributor.author | 정윤섭 | - |
dc.date.accessioned | 2015-04-23T17:25:00Z | - |
dc.date.available | 2015-04-23T17:25:00Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102422 | - |
dc.description.abstract | Increase in multidrug-resistant Acinetobacter poses a serious problem in Korea. In this study, 190 imipenem (IPM)-nonsusceptible (NS) Acinetobacter isolates from 12 Korean hospitals in 2007 were used to determine species, prevalence, and antimicrobial susceptibility of OXA carbapenemase- and metallo-β-lactamase (MBL)-producing isolates. bla(OXA)-₂₃-like and ISAba1-asssociated bla(OXA)-₅₁-like genes were detected in 80% and 12% of 178 IPM-NS Acinetobacter baumannii isolates, respectively. A novel bla(OXA)-₁₈₂ was detected in 12 IPM-NS A. baumannii isolates. Twelve out of 14 MBL-producing isolates were non-baumanniiAcinetobacter. A. baumannii isolates with OXA carbapenemase were more often resistant to aminoglycosides, ciprofloxacin, and tigecycline than non-baumannii Acinetobacter isolates with MBL. Identical pulsed- field gel electrophoresis patterns were observed in 89% of A. baumannii isolates with bla(OXA)-₂₃-like gene. In conclusion, extremely rapid increase of IPM-NS A. baumannii in previous Korean studies was mainly due to clonal spread of OXA-23-producing A. baumannii isolates. A novel OXA-182 emerged in Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 432~438 | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acinetobacter/classification | - |
dc.subject.MESH | Acinetobacter/drug effects | - |
dc.subject.MESH | Acinetobacter/enzymology* | - |
dc.subject.MESH | Acinetobacter/isolation & purification | - |
dc.subject.MESH | Acinetobacter Infections/epidemiology* | - |
dc.subject.MESH | Acinetobacter Infections/microbiology | - |
dc.subject.MESH | Amino Acid Sequence | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology* | - |
dc.subject.MESH | Bacterial Proteins/biosynthesis | - |
dc.subject.MESH | Bacterial Proteins/chemistry | - |
dc.subject.MESH | Bacterial Proteins/classification | - |
dc.subject.MESH | Bacterial Proteins/genetics* | - |
dc.subject.MESH | DNA, Bacterial/analysis | - |
dc.subject.MESH | DNA, Bacterial/genetics | - |
dc.subject.MESH | Drug Resistance, Bacterial/genetics* | - |
dc.subject.MESH | Genetic Variation | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Imipenem/pharmacology* | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Molecular Sequence Data | - |
dc.subject.MESH | Polymerase Chain Reaction/methods | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Species Specificity | - |
dc.subject.MESH | beta-Lactamases/biosynthesis | - |
dc.subject.MESH | beta-Lactamases/chemistry | - |
dc.subject.MESH | beta-Lactamases/classification | - |
dc.subject.MESH | beta-Lactamases/genetics* | - |
dc.title | Prevalence and diversity of carbapenemases among imipenem-nonsusceptible Acinetobacter isolates in Korea: emergence of a novel OXA-182. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Chang-Ki Kim | - |
dc.contributor.googleauthor | Yangsoon Lee | - |
dc.contributor.googleauthor | Hyukmin Lee | - |
dc.contributor.googleauthor | Gun-Jo Woo | - |
dc.contributor.googleauthor | Wonkeun Song | - |
dc.contributor.googleauthor | Mi-Na Kim | - |
dc.contributor.googleauthor | Wee-Gyo Lee | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | Yunsop Chon | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2010.07.014 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01038 | - |
dc.contributor.localId | A02649 | - |
dc.contributor.localId | A02947 | - |
dc.contributor.localId | A03286 | - |
dc.contributor.localId | A03619 | - |
dc.contributor.localId | A03679 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 20884158 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0732889310002889 | - |
dc.subject.keyword | OXA carbapenemase | - |
dc.subject.keyword | OXA-182 | - |
dc.subject.keyword | Metallo-β-lactamase | - |
dc.subject.keyword | Acinetobacter baumannii | - |
dc.subject.keyword | Acinetobacter genomospecies | - |
dc.subject.keyword | Korea | - |
dc.contributor.alternativeName | Kim, Chang Ki | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.alternativeName | Lee, Yang Soon | - |
dc.contributor.alternativeName | Lee, Hyuk Min | - |
dc.contributor.alternativeName | Jeong, Seok Hoon | - |
dc.contributor.alternativeName | Chong, Yun Sop | - |
dc.contributor.affiliatedAuthor | Kim, Chang Ki | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Lee, Yang Soon | - |
dc.contributor.affiliatedAuthor | Lee, Hyuk Min | - |
dc.contributor.affiliatedAuthor | Jeong, Seok Hoon | - |
dc.contributor.affiliatedAuthor | Chong, Yun Sop | - |
dc.citation.volume | 68 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 432 | - |
dc.citation.endPage | 438 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.68(4) : 432-438, 2010 | - |
dc.identifier.rimsid | 57318 | - |
dc.type.rims | ART | - |
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