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Comparative in vitro activities of torezolid (DA-7157) against clinical isolates of aerobic and anaerobic bacteria in South Korea.

Authors
 Jong Hwa Yum  ;  Sung Hak Choi  ;  Dongeun Yong  ;  Yunsop Chong  ;  Weon Bin Im  ;  Dong-Kwon Rhee  ;  Kyungwon Lee 
Citation
 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol.54(12) : 5381-5386, 2010 
Journal Title
 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 
ISSN
 0066-4804 
Issue Date
2010
MeSH
Acetamides/chemistry ; Acetamides/pharmacology ; Anti-Bacterial Agents/pharmacology* ; Bacteria, Aerobic/drug effects* ; Bacteria, Anaerobic/drug effects* ; Linezolid ; Molecular Structure ; Oxazolidinones/chemistry ; Oxazolidinones/pharmacology* ; Republic of Korea ; Tetrazoles/chemistry ; Tetrazoles/pharmacology*
Abstract
Resistance of Gram-positive pathogens to first-line antimicrobial agents has been increasing in many parts of the world. We compared the in vitro activities of torezolid with those of other antimicrobial agents, including linezolid, against clinical isolates of major aerobic and anaerobic bacteria. Torezolid had an MIC(90) of ≤0.5 μg/ml for the Gram-positive bacterial isolates tested and was more potent than either linezolid or vancomycin
Files in This Item:
T201003635.pdf Download
DOI
10.1128/AAC.00728-10
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
Chong, Yun Sop(정윤섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102408
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