Cited 11 times in
Electroencephalography features of primary epileptogenic regions in surgically treated MRI-negative infantile spasms.
DC Field | Value | Language |
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dc.contributor.author | 김동석 | - |
dc.contributor.author | 김흥동 | - |
dc.contributor.author | 이준수 | - |
dc.date.accessioned | 2015-04-23T17:19:05Z | - |
dc.date.available | 2015-04-23T17:19:05Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1016-2291 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102233 | - |
dc.description.abstract | OBJECTIVE: To evaluate the surgical outcome for intractable, MRI-negative infantile spasms (IS), and to identify diagnostic targets in the focal epileptogenic area by methods other than MRI. METHODS: We retrospectively studied 9 patients who had had surgery for intractable IS, and whose lesions did not appear on MRI. We analyzed video/electroencephalography (EEG), single photon emission computed tomography (SPECT) and positron emission tomography (PET) findings and their surgical outcomes. In 7 patients who were seizure free after surgery, we analyzed the EEG parameters for characteristics expected in the primary epileptogenic region. RESULTS: All patients underwent resective surgery including frontal lobectomy and multilobar resection. Seven patients showed an Engel class I outcome, and 2 patients showed a class III outcome. Interictal SPECT results showed 66.7% concordance for the hemisphere affected (lateralization), and 55.6% for lesion location (localization). Ictal SPECT showed 71.4% concordance for lateralization and localization. PET showed 66.7% concordance for lateralization, and 55.6% for localization. EEG parameters, including localized paroxysmal fast activities, spindle-shaped fast activities, repetitive or rhythmic sharp/spike wave discharges, and subclinical seizures showed highly localized specificity, and may serve to identify the epileptogenic lesion. CONCLUSION: Surgical treatment of MRI-negative IS should be justified using a combination of diagnostic methods | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 182~187 | - |
dc.relation.isPartOf | PEDIATRIC NEUROSURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Electroencephalography* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Frontal Lobe/surgery* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neurosurgical Procedures/methods | - |
dc.subject.MESH | Positron-Emission Tomography | - |
dc.subject.MESH | Postoperative Complications/diagnosis | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Spasms, Infantile/classification | - |
dc.subject.MESH | Spasms, Infantile/diagnosis* | - |
dc.subject.MESH | Spasms, Infantile/surgery* | - |
dc.subject.MESH | Tomography, Emission-Computed, Single-Photon | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Electroencephalography features of primary epileptogenic regions in surgically treated MRI-negative infantile spasms. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Hur Y.J. | - |
dc.contributor.googleauthor | Lee J.S. | - |
dc.contributor.googleauthor | Kim D.S. | - |
dc.contributor.googleauthor | Hwang T. | - |
dc.contributor.googleauthor | Kim H.D. | - |
dc.identifier.doi | 10.1159/000321925 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00402 | - |
dc.contributor.localId | A01208 | - |
dc.contributor.localId | A03177 | - |
dc.relation.journalcode | J02490 | - |
dc.identifier.eissn | 1423-0305 | - |
dc.identifier.pmid | 20962550 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/321925 | - |
dc.subject.keyword | Infantile spasms | - |
dc.subject.keyword | Epileptogenic regions | - |
dc.subject.keyword | Electroencephalography | - |
dc.contributor.alternativeName | Kim, Dong Seok | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.alternativeName | Lee, Joon Soo | - |
dc.contributor.affiliatedAuthor | Kim, Dong Seok | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Lee, Joon Soo | - |
dc.citation.volume | 46 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 182 | - |
dc.citation.endPage | 187 | - |
dc.identifier.bibliographicCitation | PEDIATRIC NEUROSURGERY, Vol.46(3) : 182-187, 2010 | - |
dc.identifier.rimsid | 51156 | - |
dc.type.rims | ART | - |
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