Cited 12 times in
Electrocardiography as an early cardiac screening test in children with mitochondrial disease
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강훈철 | - |
dc.contributor.author | 김흥동 | - |
dc.contributor.author | 이영목 | - |
dc.contributor.author | 이준수 | - |
dc.date.accessioned | 2015-04-23T17:18:12Z | - |
dc.date.available | 2015-04-23T17:18:12Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1738-1061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102205 | - |
dc.description.abstract | PURPOSE: To evaluate myocardial conductivity to understand cardiac involvement in patients with mitochondrial disease. METHODS: We performed retrospective study on fifty-seven nonspecific mitochondrial encephalopathy patients with no clinical cardiac manifestations. The patients were diagnosed with mitochondrial respiratory chain complex defects through biochemical enzyme assays of muscle tissue. We performed standard 12-lead electrocardiography (ECG) on all patients. RESULTS: ECG abnormalities were observed in 30 patients (52.6%). Prolongation of the QTc interval (>440 ms) was seen in 19 patients (33.3%), widening of the corrected QRS interval in 15 (26.3%), and bundle branch block in four (7.0%). Atrioventricular block, premature atrial contraction and premature ventricular contraction were seen in two patients each (3.5%) and Wolff-Parkinson-White syndrome in one patient (1.8%). CONCLUSION: Given this finding, we recommend active screening with ECG in patients with mitochondrial disease even in patients without obvious cardiac manifestation | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 644~647 | - |
dc.language | Korean | - |
dc.publisher | 대한소아과학회 | - |
dc.relation.isPartOf | Korean Journal of Pediatrics | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Electrocardiography as an early cardiac screening test in children with mitochondrial disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Ran Baik | - |
dc.contributor.googleauthor | Jung Hyun Chae | - |
dc.contributor.googleauthor | Young Mock Lee | - |
dc.contributor.googleauthor | Hoon Chul Kang | - |
dc.contributor.googleauthor | Joon Soo Lee | - |
dc.contributor.googleauthor | Heung Dong Kim | - |
dc.identifier.doi | 10.3345/kjp.2010.53.5.644 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00102 | - |
dc.contributor.localId | A01208 | - |
dc.contributor.localId | A02955 | - |
dc.contributor.localId | A03177 | - |
dc.relation.journalcode | J02100 | - |
dc.identifier.eissn | 2092-7258 | - |
dc.identifier.pmid | 21189931 | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Conductivity | - |
dc.subject.keyword | Electrocardiography | - |
dc.subject.keyword | Heart | - |
dc.subject.keyword | Mitochondria | - |
dc.subject.keyword | Respiratory chain | - |
dc.contributor.alternativeName | Kang, Hoon Chul | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.alternativeName | Lee, Young Mock | - |
dc.contributor.alternativeName | Lee, Joon Soo | - |
dc.contributor.affiliatedAuthor | Kang, Hoon Chul | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Lee, Young Mock | - |
dc.contributor.affiliatedAuthor | Lee, Joon Soo | - |
dc.citation.volume | 53 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 644 | - |
dc.citation.endPage | 647 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatrics, Vol.53(5) : 644-647, 2010 | - |
dc.identifier.rimsid | 51135 | - |
dc.type.rims | ART | - |
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