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The impact of steatosis on liver stiffness measurement in patients with chronic hepatitis B.

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dc.contributor.author김도영-
dc.contributor.author김승업-
dc.contributor.author김희만-
dc.contributor.author박영년-
dc.contributor.author박준용-
dc.contributor.author안상훈-
dc.contributor.author이중민-
dc.contributor.author전재윤-
dc.contributor.author한광협-
dc.date.accessioned2015-04-23T17:17:36Z-
dc.date.available2015-04-23T17:17:36Z-
dc.date.issued2010-
dc.identifier.issn0172-6390-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/102186-
dc.description.abstractBACKGROUND/AIMS: Recently, several studies have indicated that liver stiffness measurement (LSM) using FibroScan accurately predicts liver fibrosis. This study investigated the impact of steatosis on LSM in patients with chronic hepatitis B (CHB). METHODOLOGY: The study prospectively enrolled 162 patients (106 men and 56 women) with CHB who underwent both a liver biopsy and LSM between January 2005 and June 2008. We examined the overall univariate correlation between steatosis and LSM value and also performed a multivariate regression analysis to identify independent variables influencing LSM values. RESULTS: The mean age of the patients was 44.4 years and the mean body mass index was 23.3 +/- 2.8kg/m2. The fibrosis stage ranged from F1 to F4 in 16 patients (9.9%), 37 (22.8%), 17 (10.5%) and 92 (56.8%), respectively. Steatosis was S0 in 128 patients (79.0%), S1 in 28 (17.3%), S2 in 6 (3.7%) and S3 in none. No overall significant correlation was noted between LSM value and steatosis (r = 0.023, p = 0.770). In the multivariate linear regression analysis, only fibrosis stage showed statistical significance (r = 0.268, p < 0.001), while steatosis did not (r = 0.013, p = 0.841). CONCLUSIONS: Our findings suggest that mild to moderate steatosis does not have a significant impact on LSM values in patients with CHB.-
dc.description.statementOfResponsibilityopen-
dc.format.extent832~838-
dc.relation.isPartOfHEPATO-GASTROENTEROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHComorbidity-
dc.subject.MESHElasticity-
dc.subject.MESHFatty Liver/epidemiology-
dc.subject.MESHFatty Liver/pathology*-
dc.subject.MESHFemale-
dc.subject.MESHHepatitis B, Chronic/epidemiology-
dc.subject.MESHHepatitis B, Chronic/pathology*-
dc.subject.MESHHumans-
dc.subject.MESHLinear Models-
dc.subject.MESHLiver/pathology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHProspective Studies-
dc.titleThe impact of steatosis on liver stiffness measurement in patients with chronic hepatitis B.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorSeung Up Kim-
dc.contributor.googleauthorDo Young Kim-
dc.contributor.googleauthorSang Hoon Ahn-
dc.contributor.googleauthorHee Man Kim-
dc.contributor.googleauthorJung Min Lee-
dc.contributor.googleauthorChae Yoon Chon-
dc.contributor.googleauthorYoung Nyun Park-
dc.contributor.googleauthorHan Kwang-Hyub-
dc.contributor.googleauthorJun Yong Park-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00654-
dc.contributor.localIdA01210-
dc.contributor.localIdA01563-
dc.contributor.localIdA01675-
dc.contributor.localIdA02226-
dc.contributor.localIdA04268-
dc.contributor.localIdA03184-
dc.contributor.localIdA03544-
dc.contributor.localIdA00385-
dc.relation.journalcodeJ00984-
dc.identifier.pmid21033238-
dc.contributor.alternativeNameKim, Do Young-
dc.contributor.alternativeNameKim, Seung Up-
dc.contributor.alternativeNameKim, Hee Man-
dc.contributor.alternativeNamePark, Young Nyun-
dc.contributor.alternativeNamePark, Jun Yong-
dc.contributor.alternativeNameAhn, Sang Hoon-
dc.contributor.alternativeNameLee, Jung Min-
dc.contributor.alternativeNameChon, Chae Yoon-
dc.contributor.alternativeNameHan, Kwang Hyup-
dc.contributor.affiliatedAuthorKim, Seung Up-
dc.contributor.affiliatedAuthorKim, Hee Man-
dc.contributor.affiliatedAuthorPark, Young Nyun-
dc.contributor.affiliatedAuthorPark, Jun Yong-
dc.contributor.affiliatedAuthorAhn, Sang Hoon-
dc.contributor.affiliatedAuthorHan, Kwang Hyup-
dc.contributor.affiliatedAuthorLee, Jung Min-
dc.contributor.affiliatedAuthorChon, Chae Yoon-
dc.contributor.affiliatedAuthorKim, Do Young-
dc.citation.volume57-
dc.citation.number101-
dc.citation.startPage832-
dc.citation.endPage838-
dc.identifier.bibliographicCitationHEPATO-GASTROENTEROLOGY, Vol.57(101) : 832-838, 2010-
dc.identifier.rimsid50006-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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