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경증 및 중등도의 한국인 여드름 환자에서 1% Nadifloxacin 크림(Nadixa(R))의 유효성 및 안전성 평가
DC Field | Value | Language |
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dc.contributor.author | 이주희 | - |
dc.date.accessioned | 2015-04-23T17:17:01Z | - |
dc.date.available | 2015-04-23T17:17:01Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 4944-4739 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102168 | - |
dc.description.abstract | Background: Antimicrobials have been a mainstay of inflammatory acne treatment for more than 30 years. However, antibiotic-resistant propionibacteria had been isolated with increased frequency, and associated with failure to respond to antibiotic therapy. Objective: The aim of this study was to investigate the clinical efficacy and tolerance of 1% nadifloxacin cream. Methods: In the final analysis, 197 patients with mild to moderate facial acne vulgaris were enrolled. The patients were instructed to apply 1% nadifloxacin cream twice daily to the affected skin after washing the face. Following 2 and 4 weeks of treatment, patients were observed for clinical response: number of the acne lesions, Korea acne grading system (KAGS), global improvement, and occurrence of adverse reactions. Results: During 4 weeks of treatment, nadifloxacin caused significant reduction in the number of inflamed papulo-pustular lesions and open/closed comedones. In addition, significant reduction of KAGS was observed. About 96% of patients showed clinical improvement in the overall evaluation of the therapeutic effect by physicians. All reported adverse events were mild. Conclusion: This study shows that 1% nadifloxacin cream can be an effective and safe treatment for mild to moderate acne vulgaris. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 665~671 | - |
dc.relation.isPartOf | Korean Journal of Dermatology (대한피부과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 경증 및 중등도의 한국인 여드름 환자에서 1% Nadifloxacin 크림(Nadixa(R))의 유효성 및 안전성 평가 | - |
dc.title.alternative | Clinical Efficacy and Tolerance of 1% Nadifloxacin Cream in the Treatment of Mild to Moderate Acne Vulgaris in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학) | - |
dc.contributor.googleauthor | 최원준 | - |
dc.contributor.googleauthor | 김광중 | - |
dc.contributor.googleauthor | 김낙인 | - |
dc.contributor.googleauthor | 계영철 | - |
dc.contributor.googleauthor | 서대헌 | - |
dc.contributor.googleauthor | 이주흥 | - |
dc.contributor.googleauthor | 김명남 | - |
dc.contributor.googleauthor | 이은소 | - |
dc.contributor.googleauthor | 이주희 | - |
dc.contributor.googleauthor | 노영석 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03171 | - |
dc.relation.journalcode | J02000 | - |
dc.subject.keyword | 1% nadifloxacin cream | - |
dc.subject.keyword | Acne | - |
dc.subject.keyword | Treatment | - |
dc.contributor.alternativeName | Lee, Ju Hee | - |
dc.contributor.affiliatedAuthor | Lee, Ju Hee | - |
dc.citation.volume | 48 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 665 | - |
dc.citation.endPage | 671 | - |
dc.identifier.bibliographicCitation | Korean Journal of Dermatology (대한피부과학회지), Vol.48(8) : 665-671, 2010 | - |
dc.identifier.rimsid | 49991 | - |
dc.type.rims | ART | - |
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