Cited 48 times in
Factors that affect the diagnostic accuracy of liver fibrosis measurement by Fibroscan in patients with chronic hepatitis B.
DC Field | Value | Language |
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dc.contributor.author | 김승업 | - |
dc.contributor.author | 김자경 | - |
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 이관식 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2015-04-23T17:13:35Z | - |
dc.date.available | 2015-04-23T17:13:35Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0269-2813 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102061 | - |
dc.description.abstract | BACKGROUND: Interquartile range/median value (IQR/M) of liver stiffness measurement (LSM) is a factor in chronic hepatitis C (CHC) leading to over estimation of fibrosis by Fibroscan. AIM: To investigate factors that affect the accuracy of LSM in chronic hepatitis B (CHB). METHODS: One hundred and ninety-nine patients were enrolled. Only procedures yielding > or =10 valid measurements were considered reliable. Liver fibrosis was evaluated using the Batts and Ludwig system. Liver biopsy (LB) specimens <15 mm were considered ineligible. RESULTS: The mean age (142 men and 57 women) was 40.1 years. A significant discordance (discordance of at least two stages between LB and LSM) was identified in 38 (19.1%) and 47 (23.6%) patients respectively, according to Marcellin et al. and Chan et al.'s cutoff values. In multivariate analyses, BMI and fibrosis stage (F0-2 vs. F3-4) were identified as independent predictors for significant discordance (P = 0.040; hazard ratio [HR], 1.126; 95% confidence interval [CI], 1.005-1.261 and P = 0.036; HR, 0.450; 95% CI, 0.213-0.949 respectively) with Marcellin et al.'s cutoffs, whereas fibrosis stage was the only independent predictor (P = 0.004; HR, 0.300; 95% CI, 0.131-0.685) with Chan's cutoffs. CONCLUSIONS: Success rate and IQR/M were not predictive factors of the accuracy for diagnosing liver fibrosis by Fibroscan in CHB. Fibrosis stage (F0-2) was the only factor to predict significant discordance between LB and LSM. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 498~505 | - |
dc.relation.isPartOf | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Biopsy | - |
dc.subject.MESH | Elasticity Imaging Techniques | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hepatitis B, Chronic/diagnostic imaging* | - |
dc.subject.MESH | Hepatitis C, Chronic/diagnostic imaging* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Cirrhosis/diagnosis | - |
dc.subject.MESH | Liver Cirrhosis/diagnostic imaging* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Factors that affect the diagnostic accuracy of liver fibrosis measurement by Fibroscan in patients with chronic hepatitis B. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | S. U. Kim | - |
dc.contributor.googleauthor | Y. S. Seo | - |
dc.contributor.googleauthor | J. Y. Cheong | - |
dc.contributor.googleauthor | M. Y. Kim | - |
dc.contributor.googleauthor | J. K. Kim | - |
dc.contributor.googleauthor | S. H. Um | - |
dc.contributor.googleauthor | S. W. Cho | - |
dc.contributor.googleauthor | S. K. Paik | - |
dc.contributor.googleauthor | K. S. Lee | - |
dc.contributor.googleauthor | K.-H. Han | - |
dc.contributor.googleauthor | S. H. Ahn | - |
dc.identifier.doi | 10.1111/j.1365-2036.2010.04353.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00654 | - |
dc.contributor.localId | A00852 | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A02666 | - |
dc.contributor.localId | A04268 | - |
dc.relation.journalcode | J00061 | - |
dc.identifier.eissn | 1365-2036 | - |
dc.identifier.pmid | 20491742 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2010.04353.x/abstract | - |
dc.contributor.alternativeName | Kim, Seung Up | - |
dc.contributor.alternativeName | Kim, Ja Kyung | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Lee, Kwan Sik | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Seung Up | - |
dc.contributor.affiliatedAuthor | Kim, Ja Kyung | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Kwan Sik | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 498 | - |
dc.citation.endPage | 505 | - |
dc.identifier.bibliographicCitation | ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol.32(3) : 498-505, 2010 | - |
dc.identifier.rimsid | 52697 | - |
dc.type.rims | ART | - |
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