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Efficacy and feasibility of radiofrequency ablation for liver metastases from gastric adenocarcinoma

DC FieldValueLanguage
dc.contributor.author이성숙-
dc.contributor.author전성하-
dc.contributor.author정현철-
dc.contributor.author정희철-
dc.contributor.author라선영-
dc.contributor.author이광훈-
dc.contributor.author안정련-
dc.contributor.author김혜련-
dc.contributor.author노성훈-
dc.date.accessioned2015-04-23T17:10:51Z-
dc.date.available2015-04-23T17:10:51Z-
dc.date.issued2010-
dc.identifier.issn0265-6736-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101974-
dc.description.abstractPURPOSE: Optimal treatment for liver metastases from gastric cancer remains a matter of debate. The aim of our study is to evaluate the efficacy of radiofrequency ablation (RFA) for the treatment of liver-only metastases from gastric adenocarcinoma. MATERIALS AND METHODS: We retrospectively reviewed medical records of 29 patients who developed liver-only metastases from gastric adenocarcinoma and subsequently underwent gastric resection and RFA (n = 20) or gastric resection and systemic chemotherapy (n = 9) between January 1995 and February 2008. Overall survival was estimated using the Kaplan-Meier method, and was compared using the log rank test to evaluate RFA efficacy. RESULTS: Twenty patients who underwent RFA showed a median overall survival of 30.7 months (range: 2.9 to 90.9 months), a median progression-free survival of 6.8 months (range: 0.8 to 45.2 months), and median overall one-, three-, and five-year survival rates were 66.8%, 40.1%, and 16.1% respectively. The RFA group showed a 76% decreased death rate compared to the chemotherapy-only group (30.7 months versus 7 months, hazard ratio, 0.24; p = 0.004). Most patients tolerated RFA well, and complications were found to be minor (transient fever (20%) and/or right upper quadrant pain (25%)). One case of treatment-related death occurred due to sepsis that originated from a liver abscess at the ablation site. CONCLUSIONS: The data suggest that a use of RFA as a liver-directed treatment may provide greater survival benefit than chemotherapy and is an alternative option for the treatment of liver-only metastases from gastric cancer.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF HYPERTHERMIA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/drug therapy-
dc.subject.MESHAdenocarcinoma/pathology-
dc.subject.MESHAdenocarcinoma/secondary-
dc.subject.MESHAdenocarcinoma/surgery*-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCatheter Ablation/adverse effects-
dc.subject.MESHCatheter Ablation/methods*-
dc.subject.MESHCatheter Ablation/mortality-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFeasibility Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHLiver Neoplasms/drug therapy-
dc.subject.MESHLiver Neoplasms/pathology-
dc.subject.MESHLiver Neoplasms/secondary-
dc.subject.MESHLiver Neoplasms/surgery*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Recurrence, Local/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHStomach Neoplasms/surgery-
dc.subject.MESHTreatment Outcome-
dc.titleEfficacy and feasibility of radiofrequency ablation for liver metastases from gastric adenocarcinoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorHye Ryun Kim-
dc.contributor.googleauthorSeong Ha Cheon-
dc.contributor.googleauthorSun Young Rha-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorHyun Cheol Chung-
dc.contributor.googleauthorSung Sook Lee-
dc.contributor.googleauthorHei-Cheul Jeung-
dc.contributor.googleauthorJung Ryun Ahn-
dc.contributor.googleauthorKwang-Hun Lee-
dc.identifier.doi10.3109/02656730903555696-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02867-
dc.contributor.localIdA03520-
dc.contributor.localIdA03773-
dc.contributor.localIdA02256-
dc.contributor.localIdA01166-
dc.contributor.localIdA01281-
dc.contributor.localIdA03794-
dc.contributor.localIdA01316-
dc.contributor.localIdA02675-
dc.relation.journalcodeJ01122-
dc.identifier.eissn1464-5157-
dc.identifier.pmid20210605-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/02656730903555696-
dc.subject.keywordradiofrequency ablation-
dc.subject.keywordgastric cancer-
dc.subject.keywordliver metastases-
dc.contributor.alternativeNameLee, Sung Sook-
dc.contributor.alternativeNameCheon, Seong Ha-
dc.contributor.alternativeNameChung, Hyun Cheol-
dc.contributor.alternativeNameJeung, Hei Cheul-
dc.contributor.alternativeNameRha, Sun Young-
dc.contributor.alternativeNameLee, Kwang Hoon-
dc.contributor.alternativeNameAhn, Jung Ryun-
dc.contributor.alternativeNameKim, Hye Ryun-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.affiliatedAuthorLee, Sung Sook-
dc.contributor.affiliatedAuthorCheon, Seong Ha-
dc.contributor.affiliatedAuthorChung, Hyun Cheol-
dc.contributor.affiliatedAuthorAhn, Jung Ryun-
dc.contributor.affiliatedAuthorKim, Hye Ryun-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorJeung, Hei Cheul-
dc.contributor.affiliatedAuthorRha, Sun Young-
dc.contributor.affiliatedAuthorLee, Kwang Hoon-
dc.citation.volume26-
dc.citation.number4-
dc.citation.startPage305-
dc.citation.endPage315-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF HYPERTHERMIA, Vol.26(4) : 305-315, 2010-
dc.identifier.rimsid50984-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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