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Optimal effect-site concentration of remifentanil for preventing cough during emergence from sevoflurane-remifentanil anaesthesia.

DC FieldValueLanguage
dc.contributor.author박원선-
dc.contributor.author송종욱-
dc.contributor.author심연희-
dc.contributor.author이종화-
dc.contributor.author전나형-
dc.date.accessioned2015-04-23T17:07:47Z-
dc.date.available2015-04-23T17:07:47Z-
dc.date.issued2010-
dc.identifier.issn0003-2409-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101876-
dc.description.abstractThis randomised, double-blinded, controlled trial was designed to identify the optimal dose of remifentanil for cough suppression without adverse effects during emergence from sevoflurane-remifentanil anaesthesia for thyroidectomy. One hundred and four patients were randomly assigned to maintain target effect-site concentrations of remifentanil at 0 (control group), 1.0 (remifentail 1 group), or 1.5 ng.ml(-1) (remifentanil 1.5 group) during emergence. The incidence of coughing was lower in the remifentanil 1.5 group (31%) than in the control group (74%) or remifentanil 1 group (63%) (p = 0.0004). In addition, the severity of coughing during extubation was lower in the remifentanil 1.5 group (median (IQR [range]) 0 (0-1 [0-1]) than in the control group (1 (0-2 [0-3])) and remifentanil 1 group (1 (0-2 [0-3])) (p = 0.004). Haemodynamic changes were reduced, but emergence time and stay in the post-anaesthesia care unit was prolonged in the remifentanil 1.5 group. Maintaining the remifentanil effect-site concentration at 1.5 ng.ml(-1) during emergence from sevoflurane-remifentanil anaesthesia reduces the incidence and severity of coughing without serious adverse events and may provide haemodynamic stability in patients undergoing thyroidectomy. However, awakening may be delayed.-
dc.description.statementOfResponsibilityopen-
dc.format.extent930~935-
dc.relation.isPartOfANAESTHESIA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAnalgesics, Opioid/administration & dosage*-
dc.subject.MESHAnalgesics, Opioid/adverse effects-
dc.subject.MESHAnesthesia Recovery Period-
dc.subject.MESHAnesthetics, Combined-
dc.subject.MESHAnesthetics, Inhalation*-
dc.subject.MESHAnesthetics, Intravenous-
dc.subject.MESHCough/prevention & control*-
dc.subject.MESHDevice Removal/adverse effects-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHDrug Administration Schedule-
dc.subject.MESHFemale-
dc.subject.MESHHemodynamics/drug effects-
dc.subject.MESHHumans-
dc.subject.MESHIntubation, Intratracheal-
dc.subject.MESHMale-
dc.subject.MESHMethyl Ethers*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPiperidines/administration & dosage*-
dc.subject.MESHPiperidines/adverse effects-
dc.subject.MESHPostoperative Complications/chemically induced-
dc.subject.MESHThyroidectomy-
dc.titleOptimal effect-site concentration of remifentanil for preventing cough during emergence from sevoflurane-remifentanil anaesthesia.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorN. H. Jun-
dc.contributor.googleauthorJ. W. Lee-
dc.contributor.googleauthorJ. W. Song-
dc.contributor.googleauthorJ. C. Koh-
dc.contributor.googleauthorW. S. Park-
dc.contributor.googleauthorY. H. Shim-
dc.identifier.doi10.1111/j.1365-2044.2010.06450.x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01590-
dc.contributor.localIdA02060-
dc.contributor.localIdA02196-
dc.contributor.localIdA03154-
dc.contributor.localIdA03505-
dc.relation.journalcodeJ00128-
dc.identifier.eissn1365-2044-
dc.identifier.pmid20645945-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2010.06450.x/abstract-
dc.contributor.alternativeNamePark, Won Sun-
dc.contributor.alternativeNameSong, Jong Wook-
dc.contributor.alternativeNameShim, Yon Hee-
dc.contributor.alternativeNameLee, Jong Wha-
dc.contributor.alternativeNameJun, Na Hyung-
dc.contributor.affiliatedAuthorPark, Won Sun-
dc.contributor.affiliatedAuthorSong, Jong Wook-
dc.contributor.affiliatedAuthorShim, Yon Hee-
dc.contributor.affiliatedAuthorLee, Jong Wha-
dc.contributor.affiliatedAuthorJun, Na Hyung-
dc.citation.volume65-
dc.citation.number9-
dc.citation.startPage930-
dc.citation.endPage935-
dc.identifier.bibliographicCitationANAESTHESIA, Vol.65(9) : 930-935, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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