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Na와 F 원소가 칼슘 포스페이트 글라스의 용해도 및 세포 활성도에 미치는 영향

DC FieldValueLanguage
dc.contributor.author김경남-
dc.contributor.author김광만-
dc.contributor.author김민철-
dc.contributor.author이병현-
dc.contributor.author이용근-
dc.date.accessioned2015-04-23T17:03:21Z-
dc.date.available2015-04-23T17:03:21Z-
dc.date.issued2010-
dc.identifier.issn1225-1631-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101738-
dc.description.abstractThe development of phosphate glasses for clinical applications has attracted much interest because their chemical and physical properties make them suitable for use as bone-graft materials. We prepared various compositions of CaO-P2O5-CaF2-Na2O glass system by conventional melting process. The objective of this work was to investigate the effect of sodium and fluorine elements on calcium phosphate glasses for bone regeneration by measuring solubility and biological response. Atomic ratio of (Ca+Na)/P and a content of P2O5 were fixed at 0.6 and 45.45 mol%, respectively. To measure solubility, the pellet was kept into 30 mL of distilled water. At the same time as the solubility measurements, the pH of the solution was also measured. Ca, P, and Na ion dissolution were measured by Inductively Coupled Plasma Atomic Emission Spectrophotometer and the release of F ion was determined using Fluoride Ion Selective Electrode. Biological response of glass extracts was measured using WST-1 method. Glasses with high content of sodium oxides showed larger solubility rate, but in case of glasses with F element, there were few changes. The dissolved amount of Ca and P ion was related to solubility; with high solubility, the dissolved amount was increased. Except for glass with CaF2 and Na2O content of each 9 mol%, with increasing added oxides content and time, the pH value tended to be lower. pH values decreased with P ion content increasing. The viability of MG 63 cell in glass extracts of 2 weeks showed above 90%.-
dc.description.statementOfResponsibilityopen-
dc.format.extent107~114-
dc.relation.isPartOfJournal of the Korean Research Society for Dental Materials (대한치과기재학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNa와 F 원소가 칼슘 포스페이트 글라스의 용해도 및 세포 활성도에 미치는 영향-
dc.title.alternativeEffect of Na and F Elements on the Solubility and Cell Viability of Calcium Phosphate Glass-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Dental Engineering (치과생체재료공학)-
dc.contributor.googleauthor김민철-
dc.contributor.googleauthor이병현-
dc.contributor.googleauthor김경남-
dc.contributor.googleauthor김광만-
dc.contributor.googleauthor이용근-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00292-
dc.contributor.localIdA00312-
dc.contributor.localIdA02799-
dc.contributor.localIdA02976-
dc.contributor.localIdA00478-
dc.relation.journalcodeJ01846-
dc.subject.keywordCalcium phosphate-
dc.subject.keywordSolubility-
dc.subject.keywordDissolution-
dc.subject.keywordIon release-
dc.subject.keywordCell viability-
dc.contributor.alternativeNameKim, Kyoung Nam-
dc.contributor.alternativeNameKim, Kwang Mahn-
dc.contributor.alternativeNameKim, Min Chul-
dc.contributor.alternativeNameLee, Byung Hyun-
dc.contributor.alternativeNameLee, Yong Keun-
dc.contributor.affiliatedAuthorKim, Kyoung Nam-
dc.contributor.affiliatedAuthorKim, Kwang Mahn-
dc.contributor.affiliatedAuthorLee, Byung Hyun-
dc.contributor.affiliatedAuthorLee, Yong Keun-
dc.contributor.affiliatedAuthorKim, Min Chul-
dc.citation.volume37-
dc.citation.number2-
dc.citation.startPage107-
dc.citation.endPage114-
dc.identifier.bibliographicCitationJournal of the Korean Research Society for Dental Materials (대한치과기재학회지), Vol.37(2) : 107-114, 2010-
dc.identifier.rimsid46700-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers

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