Cited 8 times in
Dysfunctional pancreatic beta-cells of critical stress play a more prominent role in the development of stress diabetes in critically burned Korean subjects
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이병완 | - |
dc.date.accessioned | 2015-04-23T17:02:31Z | - |
dc.date.available | 2015-04-23T17:02:31Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0026-0495 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101712 | - |
dc.description.abstract | The purposes of this study are to identify the predictive parameters for the development of stress-induced hyperglycemia and to investigate the glucose metabolic homeostasis in critically burned Korean subjects. We conducted a prospective cross-sectional study of adult patients with glucose management targeting fasting and postprandial blood glucose levels less than 140 and 200 mg/dL, respectively, in patients with unrecognized diabetes. Clinical and laboratory stress parameters and insulin secretory and sensitivity parameters were assessed. Stimulated C-peptide and 24-hour urinary free cortisol predicted new-onset stress diabetes requiring insulin therapy. The subjects requiring insulin therapy were leaner and more insulin sensitive than insulin-free subjects, without significance. Glycated hemoglobin, stimulated C-peptide, homeostasis model assessment of insulin resistance, and age had a significant influence on the mean daily dose of insulin. Our present data showed that Korean subjects with dysfunctional pancreatic beta-cells of critical stress are prone to become stress diabetic and require more insulin to control the hyperglycemia | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1307~1315 | - |
dc.relation.isPartOf | METABOLISM-CLINICAL AND EXPERIMENTAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Burns/complications* | - |
dc.subject.MESH | Burns/metabolism | - |
dc.subject.MESH | Burns/physiopathology | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/etiology* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/metabolism | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperglycemia/etiology* | - |
dc.subject.MESH | Hyperglycemia/metabolism | - |
dc.subject.MESH | Hyperglycemia/physiopathology | - |
dc.subject.MESH | Insulin/blood | - |
dc.subject.MESH | Insulin Resistance | - |
dc.subject.MESH | Insulin-Secreting Cells/metabolism* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pancreas/metabolism | - |
dc.subject.MESH | Pancreas/physiopathology* | - |
dc.subject.MESH | Postprandial Period | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Stress, Physiological* | - |
dc.title | Dysfunctional pancreatic beta-cells of critical stress play a more prominent role in the development of stress diabetes in critically burned Korean subjects | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Lee Byung-Wan | - |
dc.contributor.googleauthor | Hur Jun | - |
dc.contributor.googleauthor | Hae-Jun Yim | - |
dc.contributor.googleauthor | Jae-Bong Park | - |
dc.contributor.googleauthor | Heungjeong Woo | - |
dc.contributor.googleauthor | Hyung-Joon Yoo | - |
dc.identifier.doi | 10.1016/j.metabol.2009.11.022 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02796 | - |
dc.relation.journalcode | J02223 | - |
dc.identifier.eissn | 1532-8600 | - |
dc.identifier.pmid | 20045532 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0026049509005101 | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.citation.volume | 59 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1307 | - |
dc.citation.endPage | 1315 | - |
dc.identifier.bibliographicCitation | METABOLISM-CLINICAL AND EXPERIMENTAL, Vol.59(9) : 1307-1315, 2010 | - |
dc.identifier.rimsid | 46682 | - |
dc.type.rims | ART | - |
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