Cited 17 times in
Long-term clinical outcomes of self-expanding metal stents for treatment of malignant gastroesophageal junction obstructions and prognostic factors for stent patency: effects of anticancer treatments
DC Field | Value | Language |
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dc.contributor.author | 박재준 | - |
dc.contributor.author | 박준철 | - |
dc.contributor.author | 정재복 | - |
dc.contributor.author | 송시영 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 김범경 | - |
dc.contributor.author | 김유진 | - |
dc.contributor.author | 김지현 | - |
dc.date.accessioned | 2015-04-23T17:01:38Z | - |
dc.date.available | 2015-04-23T17:01:38Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1590-8658 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101685 | - |
dc.description.abstract | BACKGROUND: Self-expanding metal stent has emerged as an effective treatment option for malignant gastroesophageal junction obstruction. However, data on the clinicopathologic factors associated with stent patency are still lacking. AIM: To investigate the long-term clinical outcomes and prognostic factors, including treatment modalities, affecting stent patency in patients with malignant gastroesophageal junction obstruction given self-expanding metal stent insertions. METHODS: A total 89 patients who underwent self-expanding metal stent insertion for malignant gastroesophageal junction obstruction were enrolled. We analysed technical and clinical success rates, complications, and prognostic factors affecting stent patency. RESULTS: Self-expanding metal stent insertion was successful in all patients and clinical improvement was achieved in 93.3%. Stent malfunction occurred in 32.9% of patients. The median overall survival time and stent patency time were 143 (95% CI: 99-187) and 190 days (95% CI: 108-272), respectively. In multivariate analysis, radiation therapy after stent placement significantly prolonged stent patency (OR: 0.221; 95% CI: 0.055-0.884; p=0.033). A higher migration rate was observed in those patients given chemotherapy after covered self-expanding metal stent placement (no anticancer treatment: 10.0%, chemotherapy: 42.9%, chemoradiation therapy: 9.1%, p=0.042). CONCLUSIONS: Self-expanding metal stent is a feasible and effective treatment for malignant gastroesophageal junction obstruction. Radiation therapy after stent placement significantly prolongs overall stent patency and chemotherapy increases the migration rate of covered stents | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 436~440 | - |
dc.relation.isPartOf | DIGESTIVE AND LIVER DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/complications | - |
dc.subject.MESH | Adenocarcinoma/diagnosis | - |
dc.subject.MESH | Adenocarcinoma/surgery | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma, Squamous Cell/complications | - |
dc.subject.MESH | Carcinoma, Squamous Cell/diagnosis | - |
dc.subject.MESH | Carcinoma, Squamous Cell/surgery | - |
dc.subject.MESH | Endoscopy, Gastrointestinal | - |
dc.subject.MESH | Esophageal Neoplasms/complications* | - |
dc.subject.MESH | Esophageal Neoplasms/diagnosis | - |
dc.subject.MESH | Esophageal Neoplasms/surgery | - |
dc.subject.MESH | Esophagectomy/methods* | - |
dc.subject.MESH | Esophagogastric Junction/surgery* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastric Outlet Obstruction/diagnosis | - |
dc.subject.MESH | Gastric Outlet Obstruction/etiology | - |
dc.subject.MESH | Gastric Outlet Obstruction/surgery* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Prosthesis Implantation/methods* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Stents* | - |
dc.subject.MESH | Time Factors | - |
dc.title | Long-term clinical outcomes of self-expanding metal stents for treatment of malignant gastroesophageal junction obstructions and prognostic factors for stent patency: effects of anticancer treatments | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.contributor.googleauthor | Beom Kyung Kim | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Yu Jin Kim | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Si Young Song | - |
dc.contributor.googleauthor | Jae Bock Chung | - |
dc.identifier.doi | 10.1016/j.dld.2009.07.020 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A03706 | - |
dc.contributor.localId | A02035 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A00487 | - |
dc.contributor.localId | A00996 | - |
dc.contributor.localId | A00787 | - |
dc.relation.journalcode | J00735 | - |
dc.identifier.eissn | 1878-3562 | - |
dc.identifier.pmid | 19767253 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1590865809003326 | - |
dc.subject.keyword | Complication | - |
dc.subject.keyword | Gastroesophageal junction | - |
dc.subject.keyword | Malignant obstruction | - |
dc.subject.keyword | SEMS | - |
dc.subject.keyword | Stent patency | - |
dc.contributor.alternativeName | Park, Jae Jun | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Chung, Jae Bock | - |
dc.contributor.alternativeName | Song, Si Young | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Kim, Beom Kyung | - |
dc.contributor.alternativeName | Kim, Yoo Jin | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Chung, Jae Bock | - |
dc.contributor.affiliatedAuthor | Song, Si Young | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Kim, Beom Kyung | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Yoo Jin | - |
dc.citation.volume | 42 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 436 | - |
dc.citation.endPage | 440 | - |
dc.identifier.bibliographicCitation | DIGESTIVE AND LIVER DISEASE, Vol.42(6) : 436-440, 2010 | - |
dc.identifier.rimsid | 46665 | - |
dc.type.rims | ART | - |
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