Cited 6 times in
Clinical feasibility of immediate overnight switching from slow-release carbamazepine to oxcarbazepine in Korean patients with refractory partial epilepsy
DC Field | Value | Language |
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dc.contributor.author | 김원주 | - |
dc.contributor.author | 이병인 | - |
dc.contributor.author | 허경 | - |
dc.date.accessioned | 2015-04-23T16:52:48Z | - |
dc.date.available | 2015-04-23T16:52:48Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1059-1311 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101402 | - |
dc.description.abstract | We assessed the clinical variables predicting the feasibility of immediate overnight switching from slow-release carbamazepine to oxcarbazepine in Korean patients with refractory partial epilepsy. Thirty patients aged 15 years or older with refractory partial epilepsy, who had been treated with slow-release carbamazepine as monotherapy or in combination therapy, were switched overnight from slow-release carbamazepine (mean dose at switching, 900 mg/day) to oxcarbazepine. Of these 30 patients, 29 (96.7%) had been treated with a slow-release formulation of carbamazepine. The proportion of patients with polytherapy was 85.3%. Overall, 9 of 30 (30%) switched patients experienced clinically significant adverse events until 2 weeks after switching, including 2 with seizure aggravation. The only clinical variable related to the failure of overnight switching was the number of seizures at baseline | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 356~358 | - |
dc.relation.isPartOf | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anticonvulsants/administration & dosage | - |
dc.subject.MESH | Anticonvulsants/adverse effects | - |
dc.subject.MESH | Anticonvulsants/therapeutic use* | - |
dc.subject.MESH | Carbamazepine/administration & dosage | - |
dc.subject.MESH | Carbamazepine/adverse effects | - |
dc.subject.MESH | Carbamazepine/analogs & derivatives* | - |
dc.subject.MESH | Carbamazepine/therapeutic use | - |
dc.subject.MESH | Delayed-Action Preparations | - |
dc.subject.MESH | Drug Resistance | - |
dc.subject.MESH | Epilepsies, Partial/drug therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Forecasting | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Seizures/epidemiology | - |
dc.subject.MESH | Seizures/prevention & control | - |
dc.subject.MESH | Treatment Failure | - |
dc.title | Clinical feasibility of immediate overnight switching from slow-release carbamazepine to oxcarbazepine in Korean patients with refractory partial epilepsy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Sang-Ahm Lee | - |
dc.contributor.googleauthor | Kyoung Heo | - |
dc.contributor.googleauthor | Won-Joo Kim | - |
dc.contributor.googleauthor | Hong-Ki Song | - |
dc.contributor.googleauthor | Sung-Eun Kim | - |
dc.contributor.googleauthor | Sang-Ho Kim | - |
dc.contributor.googleauthor | Soon-Kee No | - |
dc.contributor.googleauthor | Byung-In Lee | - |
dc.identifier.doi | 10.1016/j.seizure.2010.05.002 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00771 | - |
dc.contributor.localId | A02797 | - |
dc.contributor.localId | A04341 | - |
dc.relation.journalcode | J02648 | - |
dc.identifier.eissn | 1532-2688 | - |
dc.identifier.pmid | 20538492 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1059131110001068 | - |
dc.subject.keyword | Carbamazepine | - |
dc.subject.keyword | Oxcarbazepine | - |
dc.subject.keyword | Switching | - |
dc.subject.keyword | Partial epilepsy | - |
dc.contributor.alternativeName | Kim, Won Joo | - |
dc.contributor.alternativeName | Lee, Byung In | - |
dc.contributor.alternativeName | Heo, Kyoung | - |
dc.contributor.affiliatedAuthor | Kim, Won Joo | - |
dc.contributor.affiliatedAuthor | Lee, Byung In | - |
dc.contributor.affiliatedAuthor | Heo, Kyoung | - |
dc.citation.volume | 19 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 356 | - |
dc.citation.endPage | 358 | - |
dc.identifier.bibliographicCitation | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, Vol.19(6) : 356-358, 2010 | - |
dc.identifier.rimsid | 51032 | - |
dc.type.rims | ART | - |
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