Cited 33 times in
Prevalence of Barrett's esophagus remains low in the Korean population: nationwide cross-sectional prospective multicenter study
DC Field | Value | Language |
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dc.contributor.author | 박효진 | - |
dc.contributor.author | 이용찬 | - |
dc.date.accessioned | 2015-04-23T16:48:15Z | - |
dc.date.available | 2015-04-23T16:48:15Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0163-2116 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101257 | - |
dc.description.abstract | PURPOSE: In contrast to the Western population, the prevalence of Barrett's esophagus (BE) is rare in the Korean population. However, the recent increase in prevalence of gastroesophageal reflux disease (GERD) may affect the prevalence of BE. The aim of this study was to survey the prevalence of BE and evaluate its risk factors. METHODS: Patients between 18 and 75 years of age who visited 11 Korean tertiary referral centers between April and July 2006 for routine upper endoscopic examination were surveyed using a symptom questionnaire. Biopsies were performed on the columnar lined epithelium (CLE) of the distal esophagus, and diagnosis was confirmed with detection of specialized intestinal metaplasia. RESULTS: The study comprised 2,048 patients (mean age 51.4 years, 965 males). The frequency of heartburn or acid regurgitation was 8.7% and 13.1%, respectively. Reflux esophagitis was diagnosed in 10.1% of patients (207 patients); however, most patients had mild reflux. CLE was found in 82 patients; however, only one patient had long-segment CLE. The prevalence of BE was 1% (21 patients). The risk factors for BE were age (P = 0.006), presence of heartburn [odds ratio (OR) 4.33, 95% confidence interval (CI) 1.66-11.34, P = 0.007], acid regurgitation (OR 3.37, 95% CI 1.35-8.42, P = 0.01), sliding hernia (OR 6.21, 95% CI 1.78-21.72, P = 0.001), and reflux esophagitis (OR 10.28, 95% CI 4.31-24.50, P < 0.0001) on univariate analysis. On multivariate analysis, presence of typical reflux symptoms (P = 0.02) and reflux esophagitis (P < 0.001) were significant. CONCLUSIONS: Prevalence of Barrett's esophagus remains low in Koreans; however, risk of developing BE has increased in patients with GERD symptoms and reflux esophagitis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1932~1939 | - |
dc.relation.isPartOf | DIGESTIVE DISEASES AND SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Distribution | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Barrett Esophagus/epidemiology* | - |
dc.subject.MESH | Barrett Esophagus/pathology* | - |
dc.subject.MESH | Barrett Esophagus/therapy | - |
dc.subject.MESH | Biopsy, Needle | - |
dc.subject.MESH | Confidence Intervals | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Esophagitis, Peptic/diagnosis | - |
dc.subject.MESH | Esophagitis, Peptic/epidemiology | - |
dc.subject.MESH | Esophagitis, Peptic/therapy | - |
dc.subject.MESH | Esophagoscopy/methods | - |
dc.subject.MESH | Gastroesophageal Reflux/diagnosis | - |
dc.subject.MESH | Gastroesophageal Reflux/epidemiology | - |
dc.subject.MESH | Gastroesophageal Reflux/therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunohistochemistry | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Sex Distribution | - |
dc.subject.MESH | Young Adult | - |
dc.title | Prevalence of Barrett's esophagus remains low in the Korean population: nationwide cross-sectional prospective multicenter study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | In Seok Lee | - |
dc.contributor.googleauthor | Suck Chei Choi | - |
dc.contributor.googleauthor | Ki Nam Shim | - |
dc.contributor.googleauthor | Sam Ryong Jee | - |
dc.contributor.googleauthor | Kyu Chan Huh | - |
dc.contributor.googleauthor | Jun Haeng Lee | - |
dc.contributor.googleauthor | Kwang Jae Lee | - |
dc.contributor.googleauthor | Hyung Seok Park | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.contributor.googleauthor | Hoon Yong Jung | - |
dc.contributor.googleauthor | Hyo Jin Park | - |
dc.identifier.doi | 10.1007/s10620-009-0984-0 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01774 | - |
dc.contributor.localId | A02988 | - |
dc.relation.journalcode | J00737 | - |
dc.identifier.eissn | 1573-2568 | - |
dc.identifier.pmid | 19798574 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10620-009-0984-0 | - |
dc.contributor.alternativeName | Park, Hyo Jin | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Park, Hyo Jin | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.citation.volume | 55 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1932 | - |
dc.citation.endPage | 1939 | - |
dc.identifier.bibliographicCitation | DIGESTIVE DISEASES AND SCIENCES, Vol.55(7) : 1932-1939, 2010 | - |
dc.identifier.rimsid | 49389 | - |
dc.type.rims | ART | - |
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