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Predictors of mortality in patients returning to dialysis after allograft loss

Authors
 Park J.T.  ;  Yoo T.H.  ;  Chang T.I.  ;  Lee J.H.  ;  Lee D.H.  ;  Kim B.S.  ;  Kang S.-W.  ;  Lee H.Y.  ;  Kim M.S.  ;  Kim S.I.  ;  Kim Y.S.  ;  Choi K.H. 
Citation
 Blood Purification, Vol.30(1) : 56-63, 2010 
Journal Title
 Blood Purification 
ISSN
 0253-5068 
Issue Date
2010
MeSH
Adult ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/mortality ; Cause of Death ; Diabetes Mellitus/mortality ; Female ; Graft Rejection/immunology* ; Graft Rejection/mortality* ; Graft Survival/immunology ; Humans ; Kidney Transplantation/immunology* ; Male ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Survival Rate ; Transplantation, Homologous/immunology ; Treatment Failure
Abstract
BACKGROUND: Although patients requiring dialysis after graft loss are increasing, data regarding the outcomes of patients on dialysis after graft loss are limited. We investigated the characteristics and risk factors for mortality in patients reinitiating dialysis after graft loss. METHODS: A retrospective analysis was done for 292 patients who reinitiated dialysis after graft loss between 1985 and 2006. RESULTS: The mean glomerular filtration rate (GFR) at dialysis reinitiation was 9.1 +/- 4.6 ml/min/1.73 m(2). Cardiovascular disease was the most common cause of death during the 67.4 +/- 50.6 months of follow-up. History of diabetes (HR 4.11, p = 0.02), new-onset diabetes after transplantation (HR 1.96, p = 0.03), Charlson comorbidity index score (HR 1.66, p = 0.03), and low serum albumin levels (HR 0.42, p = 0.03) were independent risk factors for mortality. However, GFR at dialysis reinitiation was not. CONCLUSIONS: Comorbid conditions, new-onset diabetes after transplantation, and hypoalbuminemia predicted mortality in patients who returned to dialysis after graft failure.
Full Text
http://www.karger.com/Article/FullText/317122
DOI
10.1159/000317122
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Shin Wook(강신욱) ORCID logo https://orcid.org/0000-0002-5677-4756
Kim, Myoung Soo(김명수) ORCID logo https://orcid.org/0000-0002-8975-8381
Kim, Beom Seok(김범석) ORCID logo https://orcid.org/0000-0002-5732-2583
Kim, Soon Il(김순일) ORCID logo https://orcid.org/0000-0002-0783-7538
Kim, Yu Seun(김유선) ORCID logo https://orcid.org/0000-0002-5105-1567
Park, Jung Tak(박정탁) ORCID logo https://orcid.org/0000-0002-2325-8982
Yoo, Tae Hyun(유태현) ORCID logo https://orcid.org/0000-0002-9183-4507
Lee, Dong Hyoung(이동형)
Lee, Joo Hyun(이주현)
Lee, Ho Yung(이호영)
Chang, Tae Ik(장태익)
Choi, Kyu Hun(최규헌) ORCID logo https://orcid.org/0000-0003-0095-9011
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101233
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