Cited 37 times in
Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease
DC Field | Value | Language |
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dc.contributor.author | 김남규 | - |
dc.contributor.author | 김승업 | - |
dc.contributor.author | 김원호 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 박재준 | - |
dc.contributor.author | 정문재 | - |
dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2015-04-23T16:47:21Z | - |
dc.date.available | 2015-04-23T16:47:21Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0192-0790 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101228 | - |
dc.description.abstract | BACKGROUND: The aims of this study were to evaluate the efficacy of medical treatments and to identify factors to predict clinical outcome of intestinal Behçet disease (BD) during medical treatment. METHODS: We performed a retrospective review of the medical records of 93 patients who were diagnosed and medically treated with intestinal BD at Severance Hospital, Seoul, Korea from 1992 to 2007. A therapeutic response was evaluated 8 weeks after the initiation of medical treatment, and cumulative recurrence and surgery rates were also assessed during long-term follow-up. RESULTS: The initial remission rate at 8 weeks after treatment was 66.7%. During the follow-up period, cumulative recurrence rates for intestinal BD were 24.9% at 2 years and 43.0% at 5 years. The recurrence rate was significantly higher in patients with apparent gastrointestinal symptoms at their initial presentation, volcano-type and deep intestinal ulcers, and those who failed to achieve complete remission during the initial treatment. Cumulative rates for surgery were 6.7% at 2 years and 15.1% at 5 years. The typical type of ulcers was the only predictive factor for the likelihood of surgery. CONCLUSIONS: Our study demonstrates that a considerable number of patients experience disease relapse during follow-up despite a high-remission rate after medical treatment for intestinal BD. Careful observation and intensive treatment should be carried out, especially in patients without complete remission after initial treatment, with deep and volcano-shaped ulcers, or with apparent gastrointestinal symptoms at the time of diagnosis | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | e116~e122 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adrenal Cortex Hormones/administration & dosage | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Inflammatory Agents, Non-Steroidal/administration & dosage | - |
dc.subject.MESH | Azathioprine/administration & dosage | - |
dc.subject.MESH | Behcet Syndrome*/drug therapy | - |
dc.subject.MESH | Behcet Syndrome*/pathology | - |
dc.subject.MESH | Behcet Syndrome*/prevention & control | - |
dc.subject.MESH | Behcet Syndrome*/surgery | - |
dc.subject.MESH | Colchicine/administration & dosage | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunosuppressive Agents/administration & dosage | - |
dc.subject.MESH | Intestinal Diseases*/drug therapy | - |
dc.subject.MESH | Intestinal Diseases*/pathology | - |
dc.subject.MESH | Intestinal Diseases*/surgery | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mesalamine/administration & dosage | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Ulcer*/drug therapy | - |
dc.subject.MESH | Ulcer*/pathology | - |
dc.subject.MESH | Ulcer*/surgery | - |
dc.subject.MESH | Young Adult | - |
dc.title | Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Moon Jae Chung | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Seung Up Kim | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Tae Il Kim | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.identifier.doi | 10.1097/MCG.0b013e3181c8a50f | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A00654 | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A01079 | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A03602 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J01319 | - |
dc.identifier.eissn | 1539-2031 | - |
dc.identifier.pmid | 20054283 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004836-201007000-00002&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Kim, Seung Up | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.alternativeName | Kim, Tae Il | - |
dc.contributor.alternativeName | Park, Jae Jun | - |
dc.contributor.alternativeName | Chung, Moon Jae | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Seung Up | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Kim, Tae Il | - |
dc.contributor.affiliatedAuthor | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | Chung, Moon Jae | - |
dc.contributor.affiliatedAuthor | Cheon, Jae Hee | - |
dc.citation.volume | 44 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 116 | - |
dc.citation.endPage | 122 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL GASTROENTEROLOGY, Vol.44(6) : 116-122, 2010 | - |
dc.identifier.rimsid | 52145 | - |
dc.type.rims | ART | - |
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