Cited 102 times in
Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy
DC Field | Value | Language |
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dc.contributor.author | 금기창 | - |
dc.contributor.author | 금웅섭 | - |
dc.contributor.author | 김귀언 | - |
dc.contributor.author | 이창걸 | - |
dc.contributor.author | 최은창 | - |
dc.date.accessioned | 2015-04-23T16:47:01Z | - |
dc.date.available | 2015-04-23T16:47:01Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101217 | - |
dc.description.abstract | BACKGROUND: The aim of this study was to assess the results of curative surgery with and without radiotherapy in patients with T1-2N0-1 oral tongue squamous cell carcinoma (OSCC) and to evaluate survival and prognostic factors. METHODS: Retrospective analysis of 86 patients with T1-2N0-1 OSCC who received surgery between January 2000 and December 2006. Fourteen patients (16.3%) received postoperative radiotherapy (PORT). Patient characteristics, tumor characteristics, treatment modality, failure patterns, and survival rates were analyzed. RESULTS: The median follow-up was 45 months. The five-year overall survival (OS) and disease-free survival (DFS) rates were 80.8% and 80.2%, respectively. Higher tumor grade and invasion depth > or = 0.5 cm were the significant prognostic factors affecting five-year OS and DFS (OS rate; 65% vs. 91%, p = 0.001 for grade; 66% vs. 92%, p = 0.01 for invasion depth: DFS rate; 69% vs. 88%, p = 0.005 for grade; 66% vs. 92%, p = 0.013 for invasion depth). In the risk group, there was no local failure in patients with postoperative radiotherapy. CONCLUSIONS: In T1-2N0-1 OSCC, factors that affected prognosis after primary surgery were higher tumor grade and deep invasion depth over 0.5 cm. Postoperative radiotherapy should be considered in early oral tongue cancer patients with these high-risk pathologic features | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 43 | - |
dc.relation.isPartOf | RADIATION ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma, Squamous Cell/mortality | - |
dc.subject.MESH | Carcinoma, Squamous Cell/radiotherapy* | - |
dc.subject.MESH | Carcinoma, Squamous Cell/surgery* | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Tongue Neoplasms/mortality | - |
dc.subject.MESH | Tongue Neoplasms/radiotherapy* | - |
dc.subject.MESH | Tongue Neoplasms/surgery* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Young Adult | - |
dc.title | Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학) | - |
dc.contributor.googleauthor | Su Jung Shim | - |
dc.contributor.googleauthor | Jihye Cha | - |
dc.contributor.googleauthor | Woong Sub Koom | - |
dc.contributor.googleauthor | Gwi Eon Kim | - |
dc.contributor.googleauthor | Chang Geol Lee | - |
dc.contributor.googleauthor | Eun Chang Choi | - |
dc.contributor.googleauthor | Ki Chang Keum | - |
dc.identifier.doi | 10.1186/1748-717X-5-43 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00272 | - |
dc.contributor.localId | A00273 | - |
dc.contributor.localId | A00321 | - |
dc.contributor.localId | A03240 | - |
dc.contributor.localId | A04161 | - |
dc.relation.journalcode | J02591 | - |
dc.identifier.eissn | 1748-717X | - |
dc.identifier.pmid | 20504371 | - |
dc.contributor.alternativeName | Keum, Ki Chang | - |
dc.contributor.alternativeName | Koom, Woong Sub | - |
dc.contributor.alternativeName | Kim, Gwi Eon | - |
dc.contributor.alternativeName | Lee, Chang Geol | - |
dc.contributor.alternativeName | Choi, Eun Chang | - |
dc.contributor.affiliatedAuthor | Keum, Ki Chang | - |
dc.contributor.affiliatedAuthor | Koom, Woong Sub | - |
dc.contributor.affiliatedAuthor | Kim, Gwi Eon | - |
dc.contributor.affiliatedAuthor | Lee, Chang Geol | - |
dc.contributor.affiliatedAuthor | Choi, Eun Chang | - |
dc.citation.volume | 5 | - |
dc.citation.startPage | 43 | - |
dc.identifier.bibliographicCitation | RADIATION ONCOLOGY, Vol.5 : 43, 2010 | - |
dc.identifier.rimsid | 52137 | - |
dc.type.rims | ART | - |
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