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CDK4와 hTERT를 도입한 HPV16 E6/E7 불멸화 세포의 확립

DC Field Value Language
dc.contributor.author김진-
dc.contributor.author박영진-
dc.contributor.author오봉경-
dc.date.accessioned2015-04-23T16:46:36Z-
dc.date.available2015-04-23T16:46:36Z-
dc.date.issued2010-
dc.identifier.issn1225-1577-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/101204-
dc.description.abstractHuman papillomavirus (HPV) has been classified as one of the causing factors of head and neck squamous cell carcinoma (HNSCC). However, little is known about HPV-related carcinogenesis in HNSCC. The purpose of this study is to characterize immortalized human oral keratinocyte (IHOK) transfected by HPV16 E6/E7, IHOK/hcdk4 (IHOK transfected by pLXRN-hcdk4) and IHOK/hcdk4/hTERT (IHOK transfected by pLPC-hTERT-hcdk4) to reconstitute HNSCC in vitro. Conclusively, we established a new immortalized cell lines, IHOK/hcdk4 and IHOK/hcdk4/hTERT, to understand multistep carcinogenic process of oncogenic HPV16 E6/E7 in HNSCC-
dc.description.statementOfResponsibilityopen-
dc.format.extent27~36-
dc.languageKorean-
dc.publisher대한구강악안면병리학회-
dc.relation.isPartOfKorean Journal of Oral and Maxillofacial Pathology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCDK4와 hTERT를 도입한 HPV16 E6/E7 불멸화 세포의 확립-
dc.title.alternativeEstablishment of CDK4/hTERT-Transfected HPV16 E6/E7 Immortalized Cell Lines-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Pathology (구강병리학)-
dc.contributor.googleauthor박영진-
dc.contributor.googleauthor홍두표-
dc.contributor.googleauthor김은철-
dc.contributor.googleauthor오봉경-
dc.contributor.googleauthor김진-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02369-
dc.contributor.localIdA01009-
dc.contributor.localIdA01571-1-
dc.relation.journalcodeJ02084-
dc.subject.keywordhcdk4-
dc.subject.keywordHPV16 E6/E7-
dc.subject.keywordhTERT-
dc.subject.keywordImmortalization-
dc.contributor.alternativeNameKim, Jin-
dc.contributor.alternativeNamePark, Young Jin-
dc.contributor.alternativeNameOh, Bong Kyeong-
dc.contributor.affiliatedAuthorOh, Bong Kyeong-
dc.contributor.affiliatedAuthorKim, Jin-
dc.contributor.affiliatedAuthorPark, Young Jin-
dc.citation.volume34-
dc.citation.number1-
dc.citation.startPage27-
dc.citation.endPage36-
dc.identifier.bibliographicCitationKorean Journal of Oral and Maxillofacial Pathology, Vol.34(1) : 27-36, 2010-
dc.identifier.rimsid52129-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers

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