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CDK4와 hTERT를 도입한 HPV16 E6/E7 불멸화 세포의 확립
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진 | - |
dc.contributor.author | 박영진 | - |
dc.contributor.author | 오봉경 | - |
dc.date.accessioned | 2015-04-23T16:46:36Z | - |
dc.date.available | 2015-04-23T16:46:36Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1225-1577 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101204 | - |
dc.description.abstract | Human papillomavirus (HPV) has been classified as one of the causing factors of head and neck squamous cell carcinoma (HNSCC). However, little is known about HPV-related carcinogenesis in HNSCC. The purpose of this study is to characterize immortalized human oral keratinocyte (IHOK) transfected by HPV16 E6/E7, IHOK/hcdk4 (IHOK transfected by pLXRN-hcdk4) and IHOK/hcdk4/hTERT (IHOK transfected by pLPC-hTERT-hcdk4) to reconstitute HNSCC in vitro. Conclusively, we established a new immortalized cell lines, IHOK/hcdk4 and IHOK/hcdk4/hTERT, to understand multistep carcinogenic process of oncogenic HPV16 E6/E7 in HNSCC | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 27~36 | - |
dc.language | Korean | - |
dc.publisher | 대한구강악안면병리학회 | - |
dc.relation.isPartOf | Korean Journal of Oral and Maxillofacial Pathology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | CDK4와 hTERT를 도입한 HPV16 E6/E7 불멸화 세포의 확립 | - |
dc.title.alternative | Establishment of CDK4/hTERT-Transfected HPV16 E6/E7 Immortalized Cell Lines | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Pathology (구강병리학) | - |
dc.contributor.googleauthor | 박영진 | - |
dc.contributor.googleauthor | 홍두표 | - |
dc.contributor.googleauthor | 김은철 | - |
dc.contributor.googleauthor | 오봉경 | - |
dc.contributor.googleauthor | 김진 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02369 | - |
dc.contributor.localId | A01009 | - |
dc.contributor.localId | A01571-1 | - |
dc.relation.journalcode | J02084 | - |
dc.subject.keyword | hcdk4 | - |
dc.subject.keyword | HPV16 E6/E7 | - |
dc.subject.keyword | hTERT | - |
dc.subject.keyword | Immortalization | - |
dc.contributor.alternativeName | Kim, Jin | - |
dc.contributor.alternativeName | Park, Young Jin | - |
dc.contributor.alternativeName | Oh, Bong Kyeong | - |
dc.contributor.affiliatedAuthor | Oh, Bong Kyeong | - |
dc.contributor.affiliatedAuthor | Kim, Jin | - |
dc.contributor.affiliatedAuthor | Park, Young Jin | - |
dc.citation.volume | 34 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 27 | - |
dc.citation.endPage | 36 | - |
dc.identifier.bibliographicCitation | Korean Journal of Oral and Maxillofacial Pathology, Vol.34(1) : 27-36, 2010 | - |
dc.identifier.rimsid | 52129 | - |
dc.type.rims | ART | - |
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