Cited 85 times in
Associations between lipid measures and metabolic syndrome, insulin resistance and adiponectin. - Usefulness of lipid ratios in Korean men and women
DC Field | Value | Language |
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dc.contributor.author | 김희진 | - |
dc.contributor.author | 윤지은 | - |
dc.contributor.author | 지선하 | - |
dc.date.accessioned | 2015-04-23T16:43:23Z | - |
dc.date.available | 2015-04-23T16:43:23Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101103 | - |
dc.description.abstract | BACKGROUND: Several reports have raised the possibility that newly addressed lipid measures might be superior to the traditional ones for cardiovascular risk prediction. However, data on the associations between these lipid measures with metabolic syndrome (MetS) is limited. METHODS AND RESULTS: A cross-sectional study of participants in routine health examinations was performed. The associations between lipid measure variables (total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), TC/HDL-C, LDL-C/HDL-C, TG/HDL-C ratio and non-HDL-C) and MetS, insulin resistance (IR) by homeostatic model assessment (HOMA) and adiponectin were analyzed in 6,546 participants (3,820 men; mean age 46.0+/-9.2 years in men, 44.6+/-9.5 years in women). In multivariable adjusted regression analysis, the 3 lipid ratios of TC/HDL-C, LDL-C/HDL-C and TG/HDL-C showed significant association with the number of MetS components, HOMA and log adiponectin level in both men and women without MetS (P<0.001, respectively), though these relations were weaker in participants with MetS. The mean levels of the lipid ratios also associated with increasing numbers of the MetS components, quartiles of HOMA and adiponectin. CONCLUSIONS: Lipid ratios of TC/HDL-C, LDL-C/HDL-C and TG/HDL-C, as well as TG and HDL, were consistently associated with MetS and IR in participants without MetS. Lipid ratios might be used as integrated and simple lipid measures. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 931~937 | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adiponectin/blood* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Insulin Resistance* | - |
dc.subject.MESH | Lipids/blood* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metabolic Syndrome/blood* | - |
dc.subject.MESH | Metabolic Syndrome/epidemiology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Models, Biological* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.title | Associations between lipid measures and metabolic syndrome, insulin resistance and adiponectin. - Usefulness of lipid ratios in Korean men and women | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Heejin Kimm | - |
dc.contributor.googleauthor | Sang Wha Lee | - |
dc.contributor.googleauthor | Hong Soo Lee | - |
dc.contributor.googleauthor | Kyung Won Shim | - |
dc.contributor.googleauthor | Choo Yon Cho | - |
dc.contributor.googleauthor | Ji Eun Yun | - |
dc.contributor.googleauthor | Sun Ha Jee | - |
dc.identifier.doi | 10.1253/circj.CJ-09-0571 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01226 | - |
dc.contributor.localId | A02608 | - |
dc.contributor.localId | A03965 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 20215701 | - |
dc.subject.keyword | High-density lipoprotein | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Lipids | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Triglycerides | - |
dc.contributor.alternativeName | Kimm, Hee Jin | - |
dc.contributor.alternativeName | Yun, Ji Eun | - |
dc.contributor.alternativeName | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | Kimm, Hee Jin | - |
dc.contributor.affiliatedAuthor | Yun, Ji Eun | - |
dc.contributor.affiliatedAuthor | Jee, Sun Ha | - |
dc.citation.volume | 74 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 931 | - |
dc.citation.endPage | 937 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.74(5) : 931-937, 2010 | - |
dc.identifier.rimsid | 50832 | - |
dc.type.rims | ART | - |
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