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New automated hepatitis C virus (HCV) core antigen assay as an alternative to real-time PCR for HCV RNA quantification

Authors
 Yongjung Park  ;  Jong-Han Lee  ;  Beom Seok Kim  ;  Do Young Kim  ;  Kwang-Hyub Han  ;  Hyon-Suk Kim 
Citation
 JOURNAL OF CLINICAL MICROBIOLOGY, Vol.48(6) : 2253-2256, 2010 
Journal Title
 JOURNAL OF CLINICAL MICROBIOLOGY 
ISSN
 0095-1137 
Issue Date
2010
MeSH
Antigens, Viral/blood* ; Automation/methods* ; Hepacivirus/isolation & purification* ; Humans ; RNA, Viral/blood ; Reverse Transcriptase Polymerase Chain Reaction ; Statistics as Topic ; Viral Core Proteins/blood* ; Viral Load/methods*
Abstract
An automated hepatitis C virus (HCV) antigen (Ag) assay was evaluated with clinical samples. Determination of HCV Ag and RNA levels in 282 subjects using Abbott HCV Ag and Roche Cobas TaqMan assays revealed that these two tests were highly correlated (r = 0.9464). Thus, the HCV Ag assay could be an alternative test to quantitative reverse transcription-PCR.
Files in This Item:
T201001204.pdf Download
DOI
10.1128/JCM.01856-09
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영)
Kim, Beom Seok(김범석) ORCID logo https://orcid.org/0000-0002-5732-2583
Kim, Hyon Suk(김현숙) ORCID logo https://orcid.org/0000-0001-5662-7740
Park, Yong Jung(박용정)
Lee, Jong Han(이종한)
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101036
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