147 192

Cited 0 times in

뇌하수체 선종환자의 수술 전 호르몬 변화와 propofol, remifentanil 마취제 요구량의 상관관계

DC FieldValueLanguage
dc.contributor.author김은미-
dc.contributor.author민경태-
dc.contributor.author최승호-
dc.contributor.author최은경-
dc.date.accessioned2015-04-23T16:38:57Z-
dc.date.available2015-04-23T16:38:57Z-
dc.date.issued2010-
dc.identifier.issn1975-5171-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100967-
dc.description.abstractBackground:Anesthetic requirements are affected by the preoperative levels of some hormones.This study investigated to identify the hormonal status such as plasma level and maximal secretary capacity correlating with propofol and remifentanil requirements in pituitary adenoma patients who show various hormonal secretory states perioperatively. Methods:From 51 adult female pituitary adenoma patients, preoperative basal values and maximal stimulated levels of various hormones related to the axis of hypothalamus-pituitary-target organs on combined pituitary function test were recorded.Total intravenous anesthesia using target controlled infusion with propofol and remifentanil was administered.The effect-site concentration (Ce) of propofol reaching anesthetic induction and the consumed dosages of propofol and remifentanil during operation were measured.Anesthetic maintenance was controlled within 30% of preanesthetic hemodynamic variables by remifentanil and within ranges of BIS 45 ± 10 by propofol. Spearman correlations between hormonal status and anesthetic requirements such as propofol Ce for induction, total consumed doses of propofol and remifentanil were performed with a statistical significance at P of 0.05. Results:The preoperative basal level of ACTH was correlated positively with propofol induction Ce and maintenance dose, and the maximal secretory capacity of prolactin also correlated positively with propofol induction Ce.Remifentanil consumption dose was not related with any hormones measured regardless of either preoperative basal levels or maximal secretory levels. Conclusions:Propofol requirements may be related with preoperative plasma level of ACTH or maximal secretory capacity of prolactin-
dc.description.statementOfResponsibilityopen-
dc.format.extent146~150-
dc.relation.isPartOfAnesthesia and Pain Medicine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title뇌하수체 선종환자의 수술 전 호르몬 변화와 propofol, remifentanil 마취제 요구량의 상관관계-
dc.title.alternativeCorrelations of preoperative hormonal changes with propofol and remifentanil requirements in pituitary adenoma patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthor김은미-
dc.contributor.googleauthor최은미-
dc.contributor.googleauthor최승호-
dc.contributor.googleauthor허상백-
dc.contributor.googleauthor민경태-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00803-
dc.contributor.localIdA01400-
dc.contributor.localIdA04146-
dc.contributor.localIdA04101-
dc.relation.journalcodeJ00145-
dc.subject.keywordAcupuncture-
dc.subject.keywordBullous pemphigoid-
dc.subject.keywordLocalized bullous pemphigoid-
dc.contributor.alternativeNameKim, Eun Mi-
dc.contributor.alternativeNameMin, Kyeong Tae-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.alternativeNameChoi, Eun Kyeong-
dc.contributor.affiliatedAuthorKim, Eun Mi-
dc.contributor.affiliatedAuthorMin, Kyeong Tae-
dc.contributor.affiliatedAuthorChoi, Eun Kyeong-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.citation.volume5-
dc.citation.number2-
dc.citation.startPage146-
dc.citation.endPage150-
dc.identifier.bibliographicCitationAnesthesia and Pain Medicine, Vol.5(2) : 146-150, 2010-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.