Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea.

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Authors: Sue Jung Kim ; Heejung Kim ; Younghee Seo ; Dongeun Yong ; Seok Hoon Jeong ; Yunsop Chong ; Kyungwon Lee

Citation: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.67(2) : 198-201, 2010

MeSH: Bacterial Proteins/genetics* ; Bacterial Toxins/genetics* ; Bacterial Typing Techniques ; Clostridium difficile/classification* ; Clostridium difficile/genetics ; Clostridium difficile/isolation & purification* ; Cluster Analysis ; DNA Fingerprinting ; Electrophoresis, Gel, Pulsed-Field ; Enterocolitis, Pseudomembranous/microbiology* ; Enterotoxins/deficiency* ; Genotype ; Hospitals ; Humans ; Korea ; Molecular Epidemiology ; Ribotyping

Keywords: Clostridium difficile ; Toxin A-negative ; toxin B-positive (A−B+) ; Pulsed-field gel electrophoresis (PFGE)

Abstract: A(-)B(+)Clostridium difficile strains are prevalent in Korea. We performed pulsed-field gel electrophoresis (PFGE), polymerase chain reaction ribotyping, and toxinotyping in 82 A(-)B(+) clinical isolates in Korea. PFGE showed highest discriminatory capability among the 3 methods. By PFGE, persistence of a clone was found, suggesting this clone has adapted to the hospital environment

Full Text: http://www.sciencedirect.com/science/article/pii/S0732889310000118

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

Yonsei Authors: Kim, Sue Jeong(김수정)
Kim, Heejung(김희정) https://orcid.org/0000-0002-0190-703X
Yong, Dong Eun(용동은) https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) https://orcid.org/0000-0003-3788-2134
Jeong, Seok Hoon(정석훈) https://orcid.org/0000-0001-9290-897X
Chong, Yun Sop(정윤섭)

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YUHSpace: Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea.