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Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea.

Authors
 Sue Jung Kim  ;  Heejung Kim  ;  Younghee Seo  ;  Dongeun Yong  ;  Seok Hoon Jeong  ;  Yunsop Chong  ;  Kyungwon Lee 
Citation
 DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.67(2) : 198-201, 2010 
Journal Title
 DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 
ISSN
 0732-8893 
Issue Date
2010
MeSH
Bacterial Proteins/genetics* ; Bacterial Toxins/genetics* ; Bacterial Typing Techniques ; Clostridium difficile/classification* ; Clostridium difficile/genetics ; Clostridium difficile/isolation & purification* ; Cluster Analysis ; DNA Fingerprinting ; Electrophoresis, Gel, Pulsed-Field ; Enterocolitis, Pseudomembranous/microbiology* ; Enterotoxins/deficiency* ; Genotype ; Hospitals ; Humans ; Korea ; Molecular Epidemiology ; Ribotyping
Keywords
Clostridium difficile ; Toxin A-negative ; toxin B-positive (A−B+) ; Pulsed-field gel electrophoresis (PFGE)
Abstract
A(-)B(+)Clostridium difficile strains are prevalent in Korea. We performed pulsed-field gel electrophoresis (PFGE), polymerase chain reaction ribotyping, and toxinotyping in 82 A(-)B(+) clinical isolates in Korea. PFGE showed highest discriminatory capability among the 3 methods. By PFGE, persistence of a clone was found, suggesting this clone has adapted to the hospital environment
Full Text
http://www.sciencedirect.com/science/article/pii/S0732889310000118
DOI
10.1016/j.diagmicrobio.2010.01.007
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sue Jeong(김수정)
Kim, Heejung(김희정) ORCID logo https://orcid.org/0000-0002-0190-703X
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
Jeong, Seok Hoon(정석훈) ORCID logo https://orcid.org/0000-0001-9290-897X
Chong, Yun Sop(정윤섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100954
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