Cited 9 times in
Adiponectin is independently associated with apolipoprotein B to A-1 ratio in Koreans
DC Field | Value | Language |
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dc.contributor.author | 임승길 | - |
dc.contributor.author | 조민호 | - |
dc.contributor.author | 지선하 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 김경래 | - |
dc.contributor.author | 남지선 | - |
dc.contributor.author | 박종숙 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 유정선 | - |
dc.contributor.author | 이은직 | - |
dc.contributor.author | 이현철 | - |
dc.date.accessioned | 2015-04-23T16:35:46Z | - |
dc.date.available | 2015-04-23T16:35:46Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0026-0495 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100870 | - |
dc.description.abstract | Apolipoprotein B to A-1 (apo B/A-1) ratio is reportedly a better predictor of atherosclerotic vascular disease than low-density lipoprotein cholesterol (LDL-C). The aim of this study was to assess the association of serum apo B/A-1 ratio with insulin resistance and adiponectin in patients with different grades of glucose intolerance. Patients were divided according to glucose tolerance into 3 groups: normal glucose tolerance without metabolic syndrome (n = 229), impaired fasting glucose (subjects with fasting plasma glucose level between 100 and 125 mg/dL, n = 658), and type 2 diabetes mellitus (n = 381). Serum concentrations of apo B, apo A-1, glucose, total cholesterol (TC), triglycerides, and high-density lipoprotein cholesterol (HDL-C) and adiponectin were measured. Insulin resistance was estimated by the homeostasis model assessment of insulin resistance index (HOMA-IR). There were significant differences in metabolic parameters among the groups, including waist circumference, insulin, HOMA-IR, and apo B/A-1 ratio, which increased sequentially with glucose intolerance, whereas adiponectin level decreased with increasing severity of glucose intolerance. The apo B/A-1 ratio was significantly correlated with TC, triglycerides, LDL-C, HDL-C, adiponectin, and HOMA-IR in normal glucose tolerance, impaired fasting glucose, and type 2 diabetes mellitus. Multiple regression analysis showed that apo B/A-1 ratio was significantly associated with TC, LDL-C, HDL-C, and adiponectin. In conclusion, apo B/A-1 ratio was significantly associated with insulin resistance according to glucose intolerance; and serum adiponectin was an important independent factor associated with apo B/A-1 ratio in Koreans | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 677~682 | - |
dc.relation.isPartOf | METABOLISM-CLINICAL AND EXPERIMENTAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adiponectin/blood* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Apolipoprotein A-I/blood* | - |
dc.subject.MESH | Apolipoproteins B/blood* | - |
dc.subject.MESH | Cholesterol/blood | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Glucose Intolerance | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Insulin Resistance | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Triglycerides/blood | - |
dc.title | Adiponectin is independently associated with apolipoprotein B to A-1 ratio in Koreans | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Jong Suk Park | - |
dc.contributor.googleauthor | Min Ho Cho | - |
dc.contributor.googleauthor | Ji Sun Nam | - |
dc.contributor.googleauthor | Jeong Seon Yoo | - |
dc.contributor.googleauthor | Yoon Bum Lee | - |
dc.contributor.googleauthor | Jung Min Roh | - |
dc.contributor.googleauthor | Chul Woo Ahn | - |
dc.contributor.googleauthor | Sun Ha Jee | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Eun Jig Lee | - |
dc.contributor.googleauthor | Sung Kil Lim | - |
dc.contributor.googleauthor | Kyung Rae Kim | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.identifier.doi | 10.1016/j.metabol.2009.09.013 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03819 | - |
dc.contributor.localId | A03965 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A01268 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A02499 | - |
dc.contributor.localId | A03050 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A01660 | - |
dc.relation.journalcode | J02223 | - |
dc.identifier.eissn | 1532-8600 | - |
dc.identifier.pmid | 19914667 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0026049509004004 | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cho, Min Ho | - |
dc.contributor.alternativeName | Jee, Sun Ha | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Nam, Ji Sun | - |
dc.contributor.alternativeName | Park, Jong Suk | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Yoo, Jeong Seon | - |
dc.contributor.alternativeName | Lee, Eun Jig | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Cho, Min Ho | - |
dc.contributor.affiliatedAuthor | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Rae | - |
dc.contributor.affiliatedAuthor | Nam, Ji Sun | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Yoo, Jeong Seon | - |
dc.contributor.affiliatedAuthor | Lee, Eun Jig | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Park, Jong Suk | - |
dc.citation.volume | 59 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 677 | - |
dc.citation.endPage | 682 | - |
dc.identifier.bibliographicCitation | METABOLISM-CLINICAL AND EXPERIMENTAL, Vol.59(5) : 677-682, 2010 | - |
dc.identifier.rimsid | 55274 | - |
dc.type.rims | ART | - |
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