Cited 45 times in
Fentanyl sparing effects of combined ketorolac and acetaminophen for outpatient inguinal hernia repair in children.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 길혜금 | - |
dc.contributor.author | 김원옥 | - |
dc.contributor.author | 한상원 | - |
dc.contributor.author | 홍정연 | - |
dc.date.accessioned | 2015-04-23T16:32:23Z | - |
dc.date.available | 2015-04-23T16:32:23Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0022-5347 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100768 | - |
dc.description.abstract | PURPOSE: In this prospective, randomized, double-blinded study we sought to evaluate the efficacy and safety of combined use of intravenous ketorolac and acetaminophen in small children undergoing outpatient inguinal hernia repair. MATERIALS AND METHODS: We studied 55 children 1 to 5 years old who were undergoing elective repair of unilateral inguinal hernia. After induction of general anesthesia children in the experimental group (28 patients) received 1 mg/kg ketorolac and 20 mg/kg acetaminophen intravenously. In the control group (27 patients) the same volume of saline was administered. All patients received 1 microg/kg fentanyl intravenously before incision. We also evaluated the number of patients requiring postoperative rescue fentanyl, total fentanyl consumption, pain scores and side effects. RESULTS: Significantly fewer patients receiving ketorolac-acetaminophen received postoperative rescue fentanyl compared to controls (28.6% vs 81.5%). A significantly lower total dose of fentanyl was administered to patients receiving ketorolac-acetaminophen compared to controls (0.54 vs 1.37 microg/kg). Pain scores were significantly higher in the control group immediately postoperatively but eventually decreased. The incidences of sedation use (55.6% vs 25.0%) and vomiting (33.3% vs 10.7%) were significantly higher in controls. CONCLUSIONS: Preoperative intravenous coadministration of ketorolac and acetaminophen is a simple, safe and effective method for relieving postoperative pain, and demonstrates highly significant fentanyl sparing effects in small children after outpatient inguinal hernia repair | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1551~1555 | - |
dc.relation.isPartOf | JOURNAL OF UROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acetaminophen/administration & dosage* | - |
dc.subject.MESH | Ambulatory Surgical Procedures | - |
dc.subject.MESH | Analgesics, Non-Narcotic/administration & dosage* | - |
dc.subject.MESH | Analgesics, Opioid/administration & dosage* | - |
dc.subject.MESH | Anti-Inflammatory Agents, Non-Steroidal/administration & dosage* | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Fentanyl/administration & dosage* | - |
dc.subject.MESH | Hernia, Inguinal/surgery* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infusions, Intravenous | - |
dc.subject.MESH | Ketorolac/administration & dosage* | - |
dc.subject.MESH | Pain, Postoperative/prevention & control* | - |
dc.subject.MESH | Prospective Studies | - |
dc.title | Fentanyl sparing effects of combined ketorolac and acetaminophen for outpatient inguinal hernia repair in children. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | Jeong-Yeon Hong | - |
dc.contributor.googleauthor | Sang Won Han | - |
dc.contributor.googleauthor | Won Oak Kim | - |
dc.contributor.googleauthor | Hae Keum Kil | - |
dc.identifier.doi | 10.1016/j.juro.2009.12.043 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00283 | - |
dc.contributor.localId | A00766 | - |
dc.contributor.localId | A04430 | - |
dc.contributor.localId | A04285 | - |
dc.relation.journalcode | J01921 | - |
dc.identifier.eissn | 1527-3792 | - |
dc.identifier.pmid | 20172547 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0022534709032078 | - |
dc.subject.keyword | acetaminophen | - |
dc.subject.keyword | analgesia | - |
dc.subject.keyword | ketorolac | - |
dc.subject.keyword | pain | - |
dc.subject.keyword | postoperative | - |
dc.subject.keyword | pediatrics | - |
dc.contributor.alternativeName | Kil, Hae Keum | - |
dc.contributor.alternativeName | Kim, Won Oak | - |
dc.contributor.alternativeName | Han, Sang Won | - |
dc.contributor.alternativeName | Hong, Jeong Yeon | - |
dc.contributor.affiliatedAuthor | Kil, Hae Keum | - |
dc.contributor.affiliatedAuthor | Kim, Won Oak | - |
dc.contributor.affiliatedAuthor | Hong, Jeong Yeon | - |
dc.contributor.affiliatedAuthor | Han, Sang Won | - |
dc.citation.volume | 183 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1551 | - |
dc.citation.endPage | 1555 | - |
dc.identifier.bibliographicCitation | JOURNAL OF UROLOGY, Vol.183(4) : 1551-1555, 2010 | - |
dc.identifier.rimsid | 37806 | - |
dc.type.rims | ART | - |
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