Cited 33 times in
Clinicopathological features and prognostic factors of proximal gastric carcinoma in a population with high Helicobacter pylori prevalence: a single-center, large-volume study in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김유진 | - |
dc.contributor.author | 김지현 | - |
dc.contributor.author | 김충배 | - |
dc.contributor.author | 노성훈 | - |
dc.contributor.author | 박준철 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 형우진 | - |
dc.date.accessioned | 2015-04-23T16:28:24Z | - |
dc.date.available | 2015-04-23T16:28:24Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100646 | - |
dc.description.abstract | BACKGROUND: The incidence of gastric cancers has fallen in recent decades. However, a substantial reduction in Helicobacter pylori prevalence and a substantial increase in the incidence of proximal gastric cancer (PGC) have been observed in the West and Japan, but not in other East Asian countries. The purpose of this large-volume study was to analyze prevalence, clinicopathological features, and prognosis of PGC compared with other types of gastric cancer in Korea, where there is high incidence of H. pylori infection. METHODS: Between 2000 and 2005, a total of 3,193 patients were enrolled. We analyzed clinicopathological features and survival outcomes. RESULTS: Chronological analysis showed increasing incidence of PGC over the study period. PGC patients were younger and had higher incidence of Bormann types III and IV than did distal gastric cancer (DGC) patients. Also, PGC was associated with a significantly higher proportion of poorly differentiated type, T3 and T4 stage, and positive lymph nodes compared with DGC. Peritoneal and other distant metastases were more common in PGC group than in DGC group. The 5-year survival rate was significantly lower in PGC than in DGC group, regardless of curative resection. Also, the N0 and N1 category significantly influenced the 5-year survival rate. Tumor-node-metastasis (TNM) stage, hepatic metastasis, and curative resection were significant prognostic factors in PGC patients. CONCLUSIONS: PGC has increased in incidence with the respective decline in H. pylori prevalence in Korea. Survival was worse for patients with PGC than for those with DGC, regardless of curative respectability. PGC is often diagnosed at more advanced stage than other gastric cancers, and therefore early detection is critical for successful treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 829~837 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/microbiology | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/pathology* | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/surgery | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastrectomy | - |
dc.subject.MESH | Helicobacter Infections/microbiology | - |
dc.subject.MESH | Helicobacter Infections/pathology* | - |
dc.subject.MESH | Helicobacter Infections/surgery | - |
dc.subject.MESH | Helicobacter pylori/pathogenicity* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Liver Neoplasms/microbiology | - |
dc.subject.MESH | Liver Neoplasms/secondary* | - |
dc.subject.MESH | Liver Neoplasms/surgery | - |
dc.subject.MESH | Lymph Node Excision | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Peritoneal Neoplasms/microbiology | - |
dc.subject.MESH | Peritoneal Neoplasms/secondary* | - |
dc.subject.MESH | Peritoneal Neoplasms/surgery | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Stomach Neoplasms/microbiology | - |
dc.subject.MESH | Stomach Neoplasms/pathology* | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.subject.MESH | Survival Rate | - |
dc.title | Clinicopathological features and prognostic factors of proximal gastric carcinoma in a population with high Helicobacter pylori prevalence: a single-center, large-volume study in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Yu Jin Kim | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Woo Jin Hyung | - |
dc.contributor.googleauthor | Sung Hoon Noh | - |
dc.contributor.googleauthor | Choong Bai Kim | - |
dc.identifier.doi | 10.1245/s10434-009-0785-x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01063 | - |
dc.contributor.localId | A01281 | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A04382 | - |
dc.contributor.localId | A00787 | - |
dc.contributor.localId | A00996 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 19882188 | - |
dc.identifier.url | http://link.springer.com/article/10.1245%2Fs10434-009-0785-x | - |
dc.subject.keyword | Gastric Cancer | - |
dc.subject.keyword | Pylorus Infection | - |
dc.subject.keyword | Curative Resection | - |
dc.subject.keyword | Early Gastric Cancer | - |
dc.subject.keyword | Advance Gastric Cancer | - |
dc.contributor.alternativeName | Kim, Yoo Jin | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.alternativeName | Kim, Choong Bai | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.alternativeName | Hyung, Woo Jin | - |
dc.contributor.affiliatedAuthor | Kim, Choong Bai | - |
dc.contributor.affiliatedAuthor | Noh, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Hyung, Woo Jin | - |
dc.contributor.affiliatedAuthor | Kim, Yoo Jin | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.citation.volume | 17 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 829 | - |
dc.citation.endPage | 837 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.17(3) : 829-837, 2010 | - |
dc.identifier.rimsid | 37723 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.