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Intracoronary thrombus formation after drug-eluting stents implantation: optical coherence tomographic study

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dc.contributor.author고영국-
dc.contributor.author김중선-
dc.contributor.author박상민-
dc.contributor.author심재민-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author김태훈-
dc.date.accessioned2015-04-23T16:23:40Z-
dc.date.available2015-04-23T16:23:40Z-
dc.date.issued2010-
dc.identifier.issn0002-8703-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100502-
dc.description.abstractBACKGROUND: Intracoronary thrombus formation after drug-eluting stent (DES) implantation is not sufficiently evaluated. METHODS: Optical coherence tomography (OCT) was performed in 226 patients (total DES n = 244, sirolimus-eluting stent [SES] n = 95, paclitaxel-eluting stent [PES] n = 62, zotarolimus-eluting stent [ZES] n = 87) after implantation (mean 11 months, range 3-66 months). Using OCT, we investigated the incidence and determinants of intracoronary thrombus. RESULTS: Intracoronary thrombus was detected in 35 (14%) cases (27 SES [28%], 7 PES [11%], and 1 ZES [1%], P < .001) and was associated with longer stent, smaller stent diameter, and stents at bifurcation lesions. More uncovered stent struts (26 +/- 23 vs 8 +/- 17, P < .001) and malapposed stent struts (6 +/- 14 vs 2 +/- 6, P < .001) were also associated with intracoronary thrombus. Multiple logistic regression analysis found the following determinants of intracoronary thrombus: stent length > or =28 mm (odds ratio [OR] 7.31, 95% CI 1.79-29.86, P = .01), stent diameter <3.0 mm (OR 4.38, 95% CI 1.38-13.97, P = .01), and > or =8 uncovered struts in each stent (OR 3.29, 95% CI 1.07-10.17, P = .04). CONCLUSIONS: Length, size, and types of DES may be more important than clinical factors in intracoronary thrombus formation after DES implantations.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfAMERICAN HEART JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCoronary Thrombosis/diagnosis*-
dc.subject.MESHCoronary Thrombosis/epidemiology-
dc.subject.MESHCoronary Thrombosis/etiology*-
dc.subject.MESHDrug-Eluting Stents/adverse effects*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHTime Factors-
dc.subject.MESHTomography, Optical Coherence*-
dc.titleIntracoronary thrombus formation after drug-eluting stents implantation: optical coherence tomographic study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorChunyu Fan-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorJae-Min Shim-
dc.contributor.googleauthorSang-Min Park-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi10.1016/j.ahj.2009.11.029-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00127-
dc.contributor.localIdA00961-
dc.contributor.localIdA01485-
dc.contributor.localIdA02206-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA01085-
dc.relation.journalcodeJ00069-
dc.identifier.eissn1097-6744-
dc.identifier.pmid20152227-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0002870309009545-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameKim, Tae Hoon-
dc.contributor.alternativeNamePark, Sang Min-
dc.contributor.alternativeNameShim, Jae Min-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorPark, Sang Min-
dc.contributor.affiliatedAuthorShim, Jae Min-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.contributor.affiliatedAuthorKim, Tae-Hoon-
dc.citation.volume159-
dc.citation.number2-
dc.citation.startPage278-
dc.citation.endPage283-
dc.identifier.bibliographicCitationAMERICAN HEART JOURNAL, Vol.159(2) : 278-283, 2010-
dc.identifier.rimsid36526-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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