Cited 36 times in
Undifferentiated histology after endoscopic resection may predict synchronous and metachronous occurrence of early gastric cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김유진 | - |
dc.contributor.author | 박준철 | - |
dc.contributor.author | 서주희 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.date.accessioned | 2015-04-23T16:22:02Z | - |
dc.date.available | 2015-04-23T16:22:02Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0012-2823 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100453 | - |
dc.description.abstract | BACKGROUND: Endoscopic resection (endoscopic mucosal resection, EMR, and endoscopic submucosal dissection, ESD) has been accepted worldwide as a less invasive standard treatment for early gastric cancer (EGC). However, the risk of synchronous and metachronous gastric cancer developing in the post-endoscopic resection patient has become a major problem. We investigated the incidence and characteristics of synchronous and metachronous multiple gastric cancers in a retrospective study of patients with EGC after endoscopic resection. PATIENTS AND METHODS: We studied the clinicopathological features of 235 patients with EGC who had undergone endoscopic resection and were periodically followed up using endoscopic examinations (181 with a single lesion, 34 synchronous multiple lesions, and 20 metachronous multiple lesions). RESULTS: The overall incidence of synchronous and metachronous multiple gastric cancer was 14.5 and 8.5%, respectively, during a follow-up of 12-77 (median 26.5) months. Undifferentiated histology of the primary lesion was related to the occurrence of synchronous gastric cancer (p < 0.001). Undifferentiated histology and upper location of the primary lesion were correlated with the occurrence of metachronous gastric cancer (p = 0.002, 0.001). Most synchronous and metachronous lesions were well to moderately differentiated (82.4 and 80.0%); however, the proportion with undifferentiated histology (including poorly differentiated carcinoma and signet ring cell carcinoma) in synchronous and metachronous gastric cancer was significantly higher than in single gastric cancer (p = 0.008). CONCLUSIONS: Undifferentiated histology of EGC may predict the occurrence of synchronous and metachronous lesions after endoscopic resection. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 35~42 | - |
dc.relation.isPartOf | DIGESTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/epidemiology | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/pathology | - |
dc.subject.MESH | EarlyDetection ofCancer | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastroscopy* | - |
dc.subject.MESH | Helicobacter Infections/complications | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local/epidemiology | - |
dc.subject.MESH | Neoplasm Recurrence, Local/pathology | - |
dc.subject.MESH | Neoplasms, Second Primary/epidemiology | - |
dc.subject.MESH | Neoplasms, Second Primary/pathology | - |
dc.subject.MESH | Postoperative Period | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Stomach Neoplasms/epidemiology | - |
dc.subject.MESH | Stomach Neoplasms/microbiology | - |
dc.subject.MESH | Stomach Neoplasms/pathology* | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.subject.MESH | Time Factors | - |
dc.title | Undifferentiated histology after endoscopic resection may predict synchronous and metachronous occurrence of early gastric cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Seo J.H. | - |
dc.contributor.googleauthor | Park J.C. | - |
dc.contributor.googleauthor | Kim Y.J. | - |
dc.contributor.googleauthor | Shin S.K. | - |
dc.contributor.googleauthor | Lee Y.C. | - |
dc.contributor.googleauthor | Lee S.K. | - |
dc.identifier.doi | 10.1159/000235921 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A01909 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A00787 | - |
dc.relation.journalcode | J00734 | - |
dc.identifier.eissn | 1421-9867 | - |
dc.identifier.pmid | 20029207 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/235921 | - |
dc.subject.keyword | Gastric cancer, early | - |
dc.subject.keyword | Endoscopic resection | - |
dc.subject.keyword | Synchronous cancer | - |
dc.subject.keyword | Metachronous cancer | - |
dc.contributor.alternativeName | Kim, Yoo Jin | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Seo, Ju Hee | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | Seo, Ju Hee | - |
dc.contributor.affiliatedAuthor | Shin, Sung Kwan | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | Kim, Yoo Jin | - |
dc.citation.volume | 81 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 35 | - |
dc.citation.endPage | 42 | - |
dc.identifier.bibliographicCitation | DIGESTION, Vol.81(1) : 35-42, 2010 | - |
dc.identifier.rimsid | 36497 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.