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The Additional Value of Attenuation Correction CT Acquired During 18F-FDG PET/CT in Differentiating Mature From Immature Teratomas

DC FieldValueLanguage
dc.contributor.author강원준-
dc.contributor.author윤미진-
dc.contributor.author이종두-
dc.contributor.author조응혁-
dc.date.accessioned2015-01-06T17:35:38Z-
dc.date.available2015-01-06T17:35:38Z-
dc.date.issued2014-
dc.identifier.issn0363-9762-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100270-
dc.description.abstractINTRODUCTION: Increased F-FDG uptake is often seen in soft-tissue components or in neuronal components of teratomas, which makes differentiation of mature and immature teratoma difficult using only F-FDG uptake. The distribution pattern of fat and calcification in teratomas is characteristic on CT, which can also be well seen on attenuation correction CT (AC-CT). We hypothesize that the fat and calcification distribution patterns on AC-CT taken during PET/CT will provide additional diagnostic information in differentiating between mature and immature teratomas. PATIENTS AND METHODS: This retrospective study included 34 patients (44 masses; mean age 32 ± 16.3 years, range 0.2-70 years) who underwent F-FDG PET/CT before surgical resection for teratomas. F-FDG equal to or higher than the liver was visually considered positive. AC-CT images acquired during PET/CT were reviewed for calcification and fat distribution patterns. AC-CT findings for immature teratomas were scattered fat and/or disperse coarse calcification. Pathologic results were categorized into mature and immature teratomas. SUVmax and AC-CT findings were correlated with pathologic results. RESULTS: Out of the 44 lesions, 11 teratomas were immature, with higher F-FDG uptake in these tumors (7.8 ± 4.10 vs. 2.1 ± 2.28, P < 0.001). SUVmax higher than 2.8 were 91% accurate, but fat and/or calcification patterns on AC-CT were extremely helpful in reducing false-positive findings based on F-FDG uptake alone. CONCLUSION: Characteristic fat and calcification patterns on AC-CT of PET/CT were extremely helpful in differentiating mature from immature teratomas, especially in mature teratomas with increased F-FDG uptake. This can potentially reduce unnecessary radiation exposure from additional contrast-enhanced CT.-
dc.description.statementOfResponsibilityopen-
dc.format.extentE193~E196-
dc.relation.isPartOfCLINICAL NUCLEAR MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHDemography-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHFluorodeoxyglucose F18*-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultimodal Imaging*-
dc.subject.MESHPositron-Emission Tomography*-
dc.subject.MESHTeratoma/diagnostic imaging*-
dc.subject.MESHTomography, X-Ray Computed*-
dc.subject.MESHYoung Adult-
dc.titleThe Additional Value of Attenuation Correction CT Acquired During 18F-FDG PET/CT in Differentiating Mature From Immature Teratomas-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Nuclear Medicine (핵의학)-
dc.contributor.googleauthorArthur Cho-
dc.contributor.googleauthorSe-woong Kim-
dc.contributor.googleauthorJiyoun Choi-
dc.contributor.googleauthorWonjun Kang-
dc.contributor.googleauthorJong-doo Lee-
dc.contributor.googleauthorMijin Yun-
dc.identifier.doi10.1097/RLU.0b013e3182a20d5c-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00062-
dc.contributor.localIdA02550-
dc.contributor.localIdA03138-
dc.contributor.localIdA03887-
dc.relation.journalcodeJ00595-
dc.identifier.eissn1536-0229-
dc.identifier.pmid23989446-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003072-201403000-00023&LSLINK=80&D=ovft-
dc.subject.keywordteratoma-
dc.subject.keyword18 F-FDG-
dc.subject.keywordPET/CT-
dc.subject.keywordattenuation correction CT-
dc.contributor.alternativeNameKang, Won Jun-
dc.contributor.alternativeNameYun, Mi Jin-
dc.contributor.alternativeNameLee, Jong Doo-
dc.contributor.alternativeNameCho, Arthur Eung Hyuck-
dc.contributor.affiliatedAuthorKang, Won Jun-
dc.contributor.affiliatedAuthorYun, Mi Jin-
dc.contributor.affiliatedAuthorLee, Jong Doo-
dc.contributor.affiliatedAuthorCho, Arthur Eung Hyuck-
dc.rights.accessRightsfree-
dc.citation.volume39-
dc.citation.number3-
dc.citation.startPage193-
dc.citation.endPage196-
dc.identifier.bibliographicCitationCLINICAL NUCLEAR MEDICINE, Vol.39(3) : 193-196, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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