Cited 9 times in
The Additional Value of Attenuation Correction CT Acquired During 18F-FDG PET/CT in Differentiating Mature From Immature Teratomas
DC Field | Value | Language |
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dc.contributor.author | 강원준 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 이종두 | - |
dc.contributor.author | 조응혁 | - |
dc.date.accessioned | 2015-01-06T17:35:38Z | - |
dc.date.available | 2015-01-06T17:35:38Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0363-9762 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100270 | - |
dc.description.abstract | INTRODUCTION: Increased F-FDG uptake is often seen in soft-tissue components or in neuronal components of teratomas, which makes differentiation of mature and immature teratoma difficult using only F-FDG uptake. The distribution pattern of fat and calcification in teratomas is characteristic on CT, which can also be well seen on attenuation correction CT (AC-CT). We hypothesize that the fat and calcification distribution patterns on AC-CT taken during PET/CT will provide additional diagnostic information in differentiating between mature and immature teratomas. PATIENTS AND METHODS: This retrospective study included 34 patients (44 masses; mean age 32 ± 16.3 years, range 0.2-70 years) who underwent F-FDG PET/CT before surgical resection for teratomas. F-FDG equal to or higher than the liver was visually considered positive. AC-CT images acquired during PET/CT were reviewed for calcification and fat distribution patterns. AC-CT findings for immature teratomas were scattered fat and/or disperse coarse calcification. Pathologic results were categorized into mature and immature teratomas. SUVmax and AC-CT findings were correlated with pathologic results. RESULTS: Out of the 44 lesions, 11 teratomas were immature, with higher F-FDG uptake in these tumors (7.8 ± 4.10 vs. 2.1 ± 2.28, P < 0.001). SUVmax higher than 2.8 were 91% accurate, but fat and/or calcification patterns on AC-CT were extremely helpful in reducing false-positive findings based on F-FDG uptake alone. CONCLUSION: Characteristic fat and calcification patterns on AC-CT of PET/CT were extremely helpful in differentiating mature from immature teratomas, especially in mature teratomas with increased F-FDG uptake. This can potentially reduce unnecessary radiation exposure from additional contrast-enhanced CT. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | E193~E196 | - |
dc.relation.isPartOf | CLINICAL NUCLEAR MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Demography | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | Fluorodeoxyglucose F18* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multimodal Imaging* | - |
dc.subject.MESH | Positron-Emission Tomography* | - |
dc.subject.MESH | Teratoma/diagnostic imaging* | - |
dc.subject.MESH | Tomography, X-Ray Computed* | - |
dc.subject.MESH | Young Adult | - |
dc.title | The Additional Value of Attenuation Correction CT Acquired During 18F-FDG PET/CT in Differentiating Mature From Immature Teratomas | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학) | - |
dc.contributor.googleauthor | Arthur Cho | - |
dc.contributor.googleauthor | Se-woong Kim | - |
dc.contributor.googleauthor | Jiyoun Choi | - |
dc.contributor.googleauthor | Wonjun Kang | - |
dc.contributor.googleauthor | Jong-doo Lee | - |
dc.contributor.googleauthor | Mijin Yun | - |
dc.identifier.doi | 10.1097/RLU.0b013e3182a20d5c | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00062 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A03138 | - |
dc.contributor.localId | A03887 | - |
dc.relation.journalcode | J00595 | - |
dc.identifier.eissn | 1536-0229 | - |
dc.identifier.pmid | 23989446 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003072-201403000-00023&LSLINK=80&D=ovft | - |
dc.subject.keyword | teratoma | - |
dc.subject.keyword | 18 F-FDG | - |
dc.subject.keyword | PET/CT | - |
dc.subject.keyword | attenuation correction CT | - |
dc.contributor.alternativeName | Kang, Won Jun | - |
dc.contributor.alternativeName | Yun, Mi Jin | - |
dc.contributor.alternativeName | Lee, Jong Doo | - |
dc.contributor.alternativeName | Cho, Arthur Eung Hyuck | - |
dc.contributor.affiliatedAuthor | Kang, Won Jun | - |
dc.contributor.affiliatedAuthor | Yun, Mi Jin | - |
dc.contributor.affiliatedAuthor | Lee, Jong Doo | - |
dc.contributor.affiliatedAuthor | Cho, Arthur Eung Hyuck | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 39 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 193 | - |
dc.citation.endPage | 196 | - |
dc.identifier.bibliographicCitation | CLINICAL NUCLEAR MEDICINE, Vol.39(3) : 193-196, 2014 | - |
dc.identifier.rimsid | 57562 | - |
dc.type.rims | ART | - |
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