Cited 45 times in
Role of miRNAs in bone and their potential as therapeutic targets
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임승길 | - |
dc.date.accessioned | 2015-01-06T17:29:13Z | - |
dc.date.available | 2015-01-06T17:29:13Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1471-4892 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100070 | - |
dc.description.abstract | MicroRNAs (miRNAs) are noncoding, single-stranded RNAs that regulate the expression of target genes by binding their 3'-untranslated region. miRNAs are important regulators of various biological processes, including cellular differentiation, proliferation, apoptosis, and tissue development. Furthermore, aberrant miRNA expression has emerged as an important pathomechanism in various human diseases, including osteoporosis. Thus, the therapeutic potential of miRNA has attracted great interest recently. Here, we focused on the roles of miRNAs in bone homeostasis and the potential of miRNAs as therapeutic targets. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 133~141 | - |
dc.relation.isPartOf | CURRENT OPINION IN PHARMACOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Bone and Bones/metabolism* | - |
dc.subject.MESH | Cell Proliferation | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | MicroRNAs/metabolism* | - |
dc.subject.MESH | Osteoblasts/cytology | - |
dc.subject.MESH | Osteoblasts/metabolism | - |
dc.subject.MESH | Osteoporosis/drug therapy | - |
dc.subject.MESH | Osteoporosis/genetics | - |
dc.subject.MESH | Osteoporosis/metabolism | - |
dc.title | Role of miRNAs in bone and their potential as therapeutic targets | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Kyoung Min Kim | - |
dc.contributor.googleauthor | Sung-Kil Lim | - |
dc.identifier.doi | 10.1016/j.coph.2014.05.001 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03375 | - |
dc.relation.journalcode | J00679 | - |
dc.identifier.eissn | 1471-4973 | - |
dc.identifier.pmid | 24907412 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1471489214000423 | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 16 | - |
dc.citation.startPage | 133 | - |
dc.citation.endPage | 141 | - |
dc.identifier.bibliographicCitation | CURRENT OPINION IN PHARMACOLOGY, Vol.16 : 133-141, 2014 | - |
dc.identifier.rimsid | 50120 | - |
dc.type.rims | ART | - |
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