Cited 71 times in
A Randomized Comparison of Platinum Chromium-Based Everolimus-Eluting Stents Versus Cobalt Chromium-Based Zotarolimus-Eluting Stents in All-Comers Receiving Percutaneous Coronary Intervention : HOST–ASSURE (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Safety & Effectiveness of Drug-Eluting Stents & Anti-platelet Regimen), a Randomized, Controlled, Noninferiority Trial
DC Field | Value | Language |
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dc.contributor.author | 권혁문 | - |
dc.date.accessioned | 2015-01-06T17:28:14Z | - |
dc.date.available | 2015-01-06T17:28:14Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100039 | - |
dc.description.abstract | OBJECTIVES: This study sought to test whether the newly developed platinum chromium (PtCr)-based everolimus-eluting stent (EES) is noninferior to the cobalt chromium (CoCr)-based zotarolimus-eluting stent (ZES) in all-comers receiving percutaneous coronary intervention (PCI). BACKGROUND: PtCr provides improved radial strength, conformability, and visibility compared with the CoCr alloy, but PtCr-based stents have not been tested in a wide range of patients receiving PCI. Also, recent case series have raised the issue of longitudinal stent deformation (LSD) with newer drug-eluting stents. METHODS: We randomly assigned 3,755 all-comers receiving PCI to PtCr-EES or CoCr-ZES. The primary outcome was target lesion failure (TLF) at 1-year post-PCI, defined as the composite of cardiac death, nonfatal target vessel-related myocardial infarction, and ischemia-driven target lesion revascularization. Post-hoc angiographic analysis was performed to qualitatively and quantitatively analyze LSD. RESULTS: At 1 year, TLF occurred in 2.9% and 2.9% of the population in the PtCr-EES and CoCr-ZES groups, respectively (superiority p = 0.98, noninferiority p = 0.0247). There were no significant differences in the individual components of TLF as well as the patient-oriented clinical outcome. Of 5,010 stents analyzed, LSD occurred in 0.2% and 0% in the PtCr-EES and CoCr-ZES groups, respectively (p = 0.104). There was no significant difference in post-deployment stent length ratio between the 2 stents (p = 0.352). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2805~2816 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Antineoplastic Agents | - |
dc.subject.MESH | Chromium Alloys | - |
dc.subject.MESH | Chromium Compounds | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Stenosis/diagnostic imaging | - |
dc.subject.MESH | Coronary Stenosis/drug therapy* | - |
dc.subject.MESH | Drug-Eluting Stents* | - |
dc.subject.MESH | Everolimus | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunosuppressive Agents/therapeutic use* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Percutaneous Coronary Intervention/methods* | - |
dc.subject.MESH | Platelet Aggregation Inhibitors/therapeutic use* | - |
dc.subject.MESH | Platinum Compounds | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Single-Blind Method | - |
dc.subject.MESH | Sirolimus/analogs & derivatives* | - |
dc.subject.MESH | Sirolimus/therapeutic use | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | A Randomized Comparison of Platinum Chromium-Based Everolimus-Eluting Stents Versus Cobalt Chromium-Based Zotarolimus-Eluting Stents in All-Comers Receiving Percutaneous Coronary Intervention : HOST–ASSURE (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Safety & Effectiveness of Drug-Eluting Stents & Anti-platelet Regimen), a Randomized, Controlled, Noninferiority Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Kyung Woo Park | - |
dc.contributor.googleauthor | Si-Hyuck Kang | - |
dc.contributor.googleauthor | Hyun-Jae Kang | - |
dc.contributor.googleauthor | Bon-Kwon Koo | - |
dc.contributor.googleauthor | Byoung-Eun Park | - |
dc.contributor.googleauthor | Kwang Soo Cha | - |
dc.contributor.googleauthor | Jay Young Rhew | - |
dc.contributor.googleauthor | Hui-Kyoung Jeon | - |
dc.contributor.googleauthor | Eun-Seok Shin | - |
dc.contributor.googleauthor | Ju Hyeon Oh | - |
dc.contributor.googleauthor | Myung-Ho Jeong | - |
dc.contributor.googleauthor | Sanghyun Kim | - |
dc.contributor.googleauthor | Kyung-Kuk Hwang | - |
dc.contributor.googleauthor | Jung-Han Yoon | - |
dc.contributor.googleauthor | Sung Yun Lee | - |
dc.contributor.googleauthor | Tae-Ho Park | - |
dc.contributor.googleauthor | Keon Woong Moon | - |
dc.contributor.googleauthor | Hyuck-Moon Kwon | - |
dc.contributor.googleauthor | Seung-Ho Hur | - |
dc.contributor.googleauthor | Jae-Kean Ryu | - |
dc.identifier.doi | 10.1016/j.jacc.2014.04.013 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00260 | - |
dc.relation.journalcode | J01770 | - |
dc.identifier.eissn | 1558-3597 | - |
dc.identifier.pmid | 24814486 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0735109714022062 | - |
dc.subject.keyword | all-comers trial | - |
dc.subject.keyword | clinical outcome | - |
dc.subject.keyword | drug-eluting stent(s) | - |
dc.subject.keyword | percutaneous coronary intervention | - |
dc.contributor.alternativeName | Kwon, Hyuck Moon | - |
dc.contributor.affiliatedAuthor | Kwon, Hyuck Moon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 63 | - |
dc.citation.number | 25 | - |
dc.citation.startPage | 2805 | - |
dc.citation.endPage | 2816 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol.63(25) : 2805-2816, 2014 | - |
dc.identifier.rimsid | 55455 | - |
dc.type.rims | ART | - |
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