Cited 16 times in
Postoperative radiotherapy in salivary ductal carcinoma: a single institution experience
DC Field | Value | Language |
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dc.contributor.author | 서양권 | - |
dc.contributor.author | 최은창 | - |
dc.contributor.author | 고윤우 | - |
dc.contributor.author | 금기창 | - |
dc.contributor.author | 김미선 | - |
dc.contributor.author | 김세헌 | - |
dc.contributor.author | 최서희 | - |
dc.date.accessioned | 2015-01-06T17:24:18Z | - |
dc.date.available | 2015-01-06T17:24:18Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 2234-1900 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99916 | - |
dc.description.abstract | PURPOSE: We reviewed treatment outcomes and prognostic factors for patients with salivary ductal carcinoma (SDC) treated with surgery and postoperative radiotherapy from 2005 to 2012. MATERIALS AND METHODS: A total of 16 patients were identified and 15 eligible patients were included in analysis. Median age was 61 years (range, 40 to 71 years) and 12 patients (80%) were men. Twelve patients (80%) had a tumor in the parotid gland, 9 (60%) had T3 or T4 disease, and 9 (60%) had positive nodal disease. All patients underwent surgery and postoperative radiotherapy. Postoperative radiotherapy was delivered using 3-dimensional conformal radiotherapy or intensity-modulated radiotherapy. Locoregional failure-free survival (LRFFS), distant failure-free survival (DFFS), progression-free survival (PFS), and overall survival (OS) were calculated using the Kaplan-Meier method. Differences in survival based on risk factors were tested using a log-rank test. RESULTS: Median total radiotherapy dose was 60 Gy (range, 52.5 to 63.6 Gy). Four patients received concurrent weekly chemotherapy with cisplatin. Among 10 patients who underwent surgery with neck dissection, 7 received modified radical neck dissection. With a median follow-up time of 38 months (range, 24 to 105 months), 4-year rates were 86% for LRFFS, 51% for DFFS, 46% for PFS, and 93% for OS. Local failure was observed in 2 patients (13%), and distant failure was observed in 7 (47%). The lung was the most common involved site of distant metastasis. CONCLUSION: Surgery and postoperative radiotherapy in SDC patients resulted in good local control, but high distant metastasis remained a major challenge. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | RADIATION ONCOLOGY JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Postoperative radiotherapy in salivary ductal carcinoma: a single institution experience | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학) | - |
dc.contributor.googleauthor | Tae Hyung Kim | - |
dc.contributor.googleauthor | Mi Sun Kim | - |
dc.contributor.googleauthor | Seo Hee Choi | - |
dc.contributor.googleauthor | Yang Gun Suh | - |
dc.contributor.googleauthor | Yoon Woo Koh | - |
dc.contributor.googleauthor | Se Hun Kim | - |
dc.contributor.googleauthor | Eun Chang Choi | - |
dc.contributor.googleauthor | Ki Chang Keum | - |
dc.identifier.doi | 10.3857/roj.2014.32.3.125 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01891 | - |
dc.contributor.localId | A04161 | - |
dc.contributor.localId | A00133 | - |
dc.contributor.localId | A00272 | - |
dc.contributor.localId | A00444 | - |
dc.contributor.localId | A00605 | - |
dc.relation.journalcode | J02592 | - |
dc.identifier.eissn | 2234-3164 | - |
dc.identifier.pmid | 25324983 | - |
dc.subject.keyword | Carcinoma | - |
dc.subject.keyword | Radiotherapy | - |
dc.subject.keyword | Salivary ducts | - |
dc.contributor.alternativeName | Suh, Yang Gun | - |
dc.contributor.alternativeName | Choi, Eun Chang | - |
dc.contributor.alternativeName | Kho, Yoon Woo | - |
dc.contributor.alternativeName | Keum, Ki Chang | - |
dc.contributor.alternativeName | Kim, Mi Sun | - |
dc.contributor.alternativeName | Kim, Se Heon | - |
dc.contributor.affiliatedAuthor | Suh, Yang Gun | - |
dc.contributor.affiliatedAuthor | Choi, Eun Chang | - |
dc.contributor.affiliatedAuthor | Kho, Yoon Woo | - |
dc.contributor.affiliatedAuthor | Keum, Ki Chang | - |
dc.contributor.affiliatedAuthor | Kim, Mi Sun | - |
dc.contributor.affiliatedAuthor | Kim, Se Heon | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 126 | - |
dc.citation.endPage | 131 | - |
dc.identifier.bibliographicCitation | RADIATION ONCOLOGY JOURNAL, Vol.32(3) : 126-131, 2014 | - |
dc.identifier.rimsid | 53884 | - |
dc.type.rims | ART | - |
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