Cited 19 times in
Treatment outcome of localized prostate cancer by 70 Gy hypofractionated intensity-modulated radiotherapy with a customized rectal balloon
DC Field | Value | Language |
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dc.contributor.author | 김준원 | - |
dc.contributor.author | 나군호 | - |
dc.contributor.author | 서창옥 | - |
dc.contributor.author | 양승철 | - |
dc.contributor.author | 이창걸 | - |
dc.contributor.author | 조재호 | - |
dc.contributor.author | 최영득 | - |
dc.contributor.author | 홍성준 | - |
dc.date.accessioned | 2015-01-06T17:24:14Z | - |
dc.date.available | 2015-01-06T17:24:14Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 2234-1900 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99914 | - |
dc.description.abstract | PURPOSE: We aimed to analyze the treatment outcome and long-term toxicity of 70 Gy hypofractionated intensity-modulated radiotherapy (IMRT) for localized prostate cancer using a customized rectal balloon. MATERIALS AND METHODS: We reviewed medical records of 86 prostate cancer patients who received curative radiotherapy between January 2004 and December 2011 at our institution. Patients were designated as low (12.8%), intermediate (20.9%), or high risk (66.3%). Thirty patients received a total dose of 70 Gy in 28 fractions over 5 weeks via IMRT (the Hypo-IMRT group); 56 received 70.2 Gy in 39 fractions over 7 weeks via 3-dimensional conformal radiotherapy (the CF-3DRT group, which served as a reference for comparison). A customized rectal balloon was placed in Hypo-IMRT group throughout the entire radiotherapy course. Androgen deprivation therapy was administered to 47 patients (Hypo-IMRT group, 17; CF-3DRT group, 30). Late genitourinary (GU) and gastrointestinal (GI) toxicity were evaluated according to the Radiation Therapy Oncology Group criteria. RESULTS: The median follow-up period was 74.4 months (range, 18.8 to 125.9 months). The 5-year actuarial biochemical relapse-free survival rates for low-, intermediate-, and high-risk patients were 100%, 100%, and 88.5%, respectively, for the Hypo-IMRT group and 80%, 77.8%, and 63.6%, respectively, for the CF-3DRT group (p < 0.046). No patient presented with acute or late GU toxicity ≥grade 3. Late grade 3 GI toxicity occurred in 2 patients (3.6%) in the CF-3DRT group and 1 patient (3.3%) in the Hypo-IMRT group. CONCLUSION: Hypo-IMRT with a customized rectal balloon resulted in excellent biochemical control rates with minimal toxicity in localized prostate cancer patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 187~197 | - |
dc.relation.isPartOf | RADIATION ONCOLOGY JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Treatment outcome of localized prostate cancer by 70 Gy hypofractionated intensity-modulated radiotherapy with a customized rectal balloon | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학) | - |
dc.contributor.googleauthor | Hyunjung Kim | - |
dc.contributor.googleauthor | Jun Won Kim | - |
dc.contributor.googleauthor | Sung Joon Hong | - |
dc.contributor.googleauthor | Koon Ho Rha | - |
dc.contributor.googleauthor | Chang-Geol Lee | - |
dc.contributor.googleauthor | Seung Choul Yang | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.contributor.googleauthor | Chang-Ok Suh | - |
dc.contributor.googleauthor | Jaeho Cho | - |
dc.identifier.doi | 10.3857/roj.2014.32.3.187 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03901 | - |
dc.contributor.localId | A00958 | - |
dc.contributor.localId | A01227 | - |
dc.contributor.localId | A01919 | - |
dc.contributor.localId | A02294 | - |
dc.contributor.localId | A03240 | - |
dc.contributor.localId | A04111 | - |
dc.contributor.localId | A04402 | - |
dc.relation.journalcode | J02592 | - |
dc.identifier.eissn | 2234-3164 | - |
dc.identifier.pmid | 25324991 | - |
dc.subject.keyword | Hypofractionation | - |
dc.subject.keyword | Intensity modulation | - |
dc.subject.keyword | Prostatic neoplasm | - |
dc.subject.keyword | Radiotherapy | - |
dc.subject.keyword | Rectal Balloon | - |
dc.contributor.alternativeName | Kim, Jun Won | - |
dc.contributor.alternativeName | Rha, Koon Ho | - |
dc.contributor.alternativeName | Suh, Chang Ok | - |
dc.contributor.alternativeName | Yang, Seung Choul | - |
dc.contributor.alternativeName | Lee, Chang Geol | - |
dc.contributor.alternativeName | Cho, Jae Ho | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.alternativeName | Hong, Sung Joon | - |
dc.contributor.affiliatedAuthor | Cho, Jae Ho | - |
dc.contributor.affiliatedAuthor | Kim, Jun Won | - |
dc.contributor.affiliatedAuthor | Rha, Koon Ho | - |
dc.contributor.affiliatedAuthor | Suh, Chang Ok | - |
dc.contributor.affiliatedAuthor | Yang, Seung Choul | - |
dc.contributor.affiliatedAuthor | Lee, Chang Geol | - |
dc.contributor.affiliatedAuthor | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | Hong, Sung Joon | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 187 | - |
dc.citation.endPage | 197 | - |
dc.identifier.bibliographicCitation | RADIATION ONCOLOGY JOURNAL, Vol.32(3) : 187-197, 2014 | - |
dc.identifier.rimsid | 53883 | - |
dc.type.rims | ART | - |
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