대사증후군 구성요소와 유기용제 노출과의 관계

Abstract

The purpose of this study is to detect metabolic syndrome components related to exposure of organic solvent through comparison and analysis of metabolic syndrome components between workers at the workplace exposed to organic solvent (toluene, xylene, styrene) and workers at general workplace. During the period from January to December 2010, the survey was conducted against male workers of 168,769 persons with age group 30-59 completed medical checkup, dividing workers at organic solvent exposed work place and workers of general workplace against which comparisons were carried out about the result of general characteristics, blood test. Whether exposed to organic solvent and exposed period relationship with metabolic syndrome components were identified through execution of multiple logistic regression analysis. The prevalence rate of the metabolic syndrome by age was 15.0% for the 30s, 19.8% for the 40s, 22.9% for the 50s. For the whole workers, the prevalence rate of the metabolic syndrome was 17.4% in exposed workplace and 18.4% in general workplace that was higher than the rate in exposed workplace. Even if age, drinking, smoking, exercise, region and BMI were corrected, the exposure to the organic solvent was the higher the significance of blood pressure and fasting glucose were statistically and also the longer the period of exposure was, the higher the significance of blood pressure was statistically. In this study, the exposure to the organic solvent showed a statistically significant relevance with blood pressure and fasting glucose among the metabolic syndrome components and the period of exposure showed a statistically significant relevance with blood pressure. Further researches should be conducted by prospective cohort study about the organic solvent and the metabolic syndrome components supplementing the defects.