Cited 0 times in
신이식 전 시행한 혈중 Soluble CD30 농도와 PRA 및 림프구 교차반응과의 상관성
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김명수 | - |
dc.contributor.author | 김순일 | - |
dc.contributor.author | 김유선 | - |
dc.contributor.author | 장혜경 | - |
dc.contributor.author | 주만기 | - |
dc.contributor.author | 안형준 | - |
dc.date.accessioned | 2014-12-21T17:31:19Z | - |
dc.date.available | 2014-12-21T17:31:19Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1298-1711 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/97748 | - |
dc.description.abstract | Purpose: Serum level of soluble form CD30 (sCD30), a marker for T helper 2-type cytokine-producing T cells, is used as a marker of immunologic status of pre-transplant recipient that can predict graft rejection and graft survival. This study compared pre-transplant serum sCD30 levels with conventional pre-transplant immunologic parameter, such as panel-reactive antibodies (PRA) and lymphocyte cross matching (LCM). Methods: Adult seventy two patients were enrolled this study. The blood for tests was sampled simultaneously. Measurement of serum sCD30 level was performed using enzyme-linked immunosorbent assay kit (Bender MedSystems, Co. CA, USA). We tested PRA using a commercial ELISA kit (Lambda Cell Tray Lymphocytotoxicity assay)(One Lambda Inc. CA, USA). We established LCM tests for T cells by Modified NIH (National institute center of health)/Johnson`s Method/AHG (Anti human globulin), and for B cells by warm test. Results: Mean score of sCD30 was 90.3±46.4 U/mL, ranged from 12.2 to 244.4 U/mL. There was no significant correlation between patient`s age or sex and sCD30 level. The correlation between sCD30 and mode or duration of dialysis was not statistically 63 significant clinical situation. The result of LCM didn`t show significant correlation with sCD30 level (87.3±55.7 U/mL in LCM positive group versus 91.9±41.3 U/mL in LCM negative group, P=0.696). And sCD30 level equal to or more than 86 U/mL could not predict the positive result of LCM. The positive and negative predictive value of sCD30 to LCM was merely 27.8% and 58.3% (P=0.322). Also the correlation between sCD30 level and PRA was not significant (P=1.0). Conclucion: There was no significant correlation between serum sCD30 level and conventional immunologic parameter such as PRA or LCM. That means the pre-transplant monitoring of the sCD30 level can be used as an independent immunologic parameter. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Journal of the Korean Society for Transplantation | - |
dc.publisher | Journal of the Korean Society for Transplantation | - |
dc.relation.isPartOf | Journal of the Korean Society for Transplantation | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 신이식 전 시행한 혈중 Soluble CD30 농도와 PRA 및 림프구 교차반응과의 상관성 | - |
dc.title.alternative | Pre-transplant Serum Soluble CD30 Level; Correlation with Panel Reactive Antibodies and Lymphocyte Cross Matching | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Medicine (구강내과학) | - |
dc.contributor.googleauthor | 신종현 | - |
dc.contributor.googleauthor | 장혜경 | - |
dc.contributor.googleauthor | 김유선 | - |
dc.contributor.googleauthor | 김순일 | - |
dc.contributor.googleauthor | 김명수 | - |
dc.contributor.googleauthor | 전경옥 | - |
dc.contributor.googleauthor | 김현정 | - |
dc.contributor.googleauthor | 안형준 | - |
dc.contributor.googleauthor | 주만기 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00649 | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A02273 | - |
dc.contributor.localId | A03494 | - |
dc.contributor.localId | A03949 | - |
dc.contributor.localId | A00424 | - |
dc.relation.journalcode | J01858 | - |
dc.identifier.eissn | 2508-2604 | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.alternativeName | Kim, Soon Il | - |
dc.contributor.alternativeName | Kim, Yu Seun | - |
dc.contributor.alternativeName | Chang, Hye Kyung | - |
dc.contributor.alternativeName | Joo, Man Ki | - |
dc.contributor.affiliatedAuthor | Kim, Soon Il | - |
dc.contributor.affiliatedAuthor | Kim, Yu Seun | - |
dc.contributor.affiliatedAuthor | Chang, Hye Kyung | - |
dc.contributor.affiliatedAuthor | Joo, Man Ki | - |
dc.contributor.affiliatedAuthor | Kim, Myoung Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 21 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 63 | - |
dc.citation.endPage | 68 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society for Transplantation, Vol.21(1) : 63-68, 2007 | - |
dc.identifier.rimsid | 47681 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.