3 531

Cited 15 times in

Controversies in surveillance and early diagnosis of hepatocellular carcinoma

Authors
 Kim D.Y.  ;  Kim J.W.  ;  Kuromatsu R.  ;  Ahn S.H.  ;  Torimura T.  ;  Sherman M. 
Citation
 ONCOLOGY, Vol.81(suppl 1) : 56-60, 2011 
Journal Title
ONCOLOGY
ISSN
 0030-2414 
Issue Date
2011
MeSH
Biomarkers, Tumor/analysis ; Carcinoma, Hepatocellular/diagnosis* ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/virology ; Early Detection of Cancer/methods* ; Hepacivirus/pathogenicity ; Hepatitis B/complications ; Hepatitis B/virology ; Hepatitis C/complications ; Hepatitis C/virology ; Humans ; Liver Neoplasms/diagnosis* ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/virology ; Population Surveillance/methods* ; Ultrasonography, Doppler ; alpha-Fetoproteins/analysis
Keywords
Hepatocellular carcinoma ; Surveillance ; Biomarker
Abstract
The surveillance of hepatocellular carcinoma (HCC) is an established approach to detect early cancers in patients with defined risks. However, there are still varied controversies and issues to be addressed regarding the optimal surveillance methods and interval. Moreover, there are discrepancies in the opinion or practice of HCC surveillance between Eastern and Western countries. The Western strategy of ultrasound without a biomarker such as α-fetoprotein reflects the cost-effective utilization of limited resources. On the contrary, combined measurements of biomarkers in Eastern countries are based on the assumption that increased detection of early cancers could result in an overall survival benefit. To address this complicated issue, a prospective study comparing different surveillance tests might be required. More importantly, discovery of a novel biomarker with higher performance would be an alternative.
Full Text
http://www.karger.com/Article/FullText/333261
DOI
10.1159/000333261
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영)
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95230
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links