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Controversies in surveillance and early diagnosis of hepatocellular carcinoma

Title
Controversies in surveillance and early diagnosis of hepatocellular carcinoma
Authors
Kim D.Y.;Kim J.W.;Sherman M.;Torimura T.;Ahn S.H.;Kuromatsu R.
Issue Date
2011
Journal Title
Oncology
ISSN
0030-2414
Citation
Oncology, Vol.81(suppl 1) : 56~60, 2011
Abstract
The surveillance of hepatocellular carcinoma (HCC) is an established approach to detect early cancers in patients with defined risks. However, there are still varied controversies and issues to be addressed regarding the optimal surveillance methods and interval. Moreover, there are discrepancies in the opinion or practice of HCC surveillance between Eastern and Western countries. The Western strategy of ultrasound without a biomarker such as α-fetoprotein reflects the cost-effective utilization of limited resources. On the contrary, combined measurements of biomarkers in Eastern countries are based on the assumption that increased detection of early cancers could result in an overall survival benefit. To address this complicated issue, a prospective study comparing different surveillance tests might be required. More importantly, discovery of a novel biomarker with higher performance would be an alternative.
URI
http://www.karger.com/Article/FullText/333261

http://ir.ymlib.yonsei.ac.kr/handle/22282913/95230
DOI
10.1159/000333261
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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