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자성 산화철(iron oxide) 나노입자를 이용한 DNA 센서 개발

Title
자성 산화철(iron oxide) 나노입자를 이용한 DNA 센서 개발
Other Titles
Development of DNA Sensor Using Magnetic Iron Oxide Nanoparticle
Authors
남기창;송광섭
Issue Date
2011
Journal Title
Journal of The Institute of Electronics Engineers of Korea (전자공학회논문지 - SC)
ISSN
1229-6392
Citation
Journal of The Institute of Electronics Engineers of Korea (전자공학회논문지 - SC), Vol.48(6) : 51~56, 2011
Abstract
The surface of magnetic iron oxide nanoparticles (γ-Fe₂O₃) is functionalized (-NH₂, -COOH) with bifunctional organic molecules and evaluated using FT-IR (Fourier transform infrared spectroscopy). We immobilize 21-base pair probe DNA and hybridize fluorescence-labeled (Cy5) target DNA onto the functionalized iron oxide nanoparticles. The fluorescence images obtained from a confocal microscopy show that the functionalized iron oxide nanoparticles should detect the hybridization of complementary and noncomplementary DNA.
URI
http://www.dbpia.co.kr/Article/1575089

http://ir.ymlib.yonsei.ac.kr/handle/22282913/95141
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Medical Engineering
Yonsei Authors
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