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New index for categorising cardiac reentrant wave: in silico evaluation

Authors
 E.B. Shim ; S.-B. Hong ; D. Noble ; Y.E. Earm ; H.-N. Pak ; C.-H. Youn ; C.H. Leem ; K.M. Lim 
Citation
 IET Sytems Biology, Vol.5(5) : 317~323, 2011 
Journal Title
 IET Sytems Biology 
ISSN
 1751-8849 
Issue Date
2011
Abstract
Based on the similarity between a reentrant wave in cardiac tissue and a vortex in fluid dynamics, the authors hypothesised that a new non-dimensional index, like the Reynolds number in fluid dynamics, may play a critical role in categorising reentrant wave dynamics. Therefore the goal of the present study is to devise a new index to characterise electric wave conduction in cardiac tissue and examined whether this index can be used as a biomarker for categorising the reentrant wave pattern in cardiac tissue. Similar to the procedure used to derive the Reynolds number in fluid dynamics, the authors used a non-dimensionalisation technique to obtain the new index. Its usefulness was verified using a two-dimensional simulation model of electrical wave propagation in cardiac tissue. The simulation results showed that electrical waves in cardiac tissue move into an unstable region when the index exceeds a threshold value.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94967
DOI
10.1049/iet-syb.2011.0019
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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Link
 http://digital-library.theiet.org/content/journals/10.1049/iet-syb.2011.0019
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