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Application of tissue microarray for atherectomized tissues from peripheral arterial disease

Title
 Application of tissue microarray for atherectomized tissues from peripheral arterial disease 
Authors
 Se Hoon Kim ; Dong-Min Kim ; Donghoon Choi ; Young Ho Shin ; Seung Min Song ; Seong Hwan Park ; Junjeong Choi ; Hyosup Shim 
Issue Date
2011
Journal Title
 Pathology Research and Practice 
ISSN
 0344-0338 
Citation
 Pathology Research and Practice, Vol.207(9) : 568~572, 2011 
Abstract
It is not easy to apply tissue microarray (TMA) to atherectomized tissues from peripheral arterial disease because of their physical properties. We introduce a new TMA application technique for atherectomized tissues. Using a pre-made plastic TMA cassette and TMA punch device, we successfully made the TMA block containing 40 vertically oriented atherectomized tissue samples from 10 patients. The histogram of surface areas of tissue cores in the TMA showed a bell-shaped distribution, whereas that of conventionally embedded tissues showed wide distribution. This finding suggests that the TMA method might be a better way of vertical embedding than the conventional method. A TMA block prepared by our method enabled a simultaneous evaluation of the histopathology of vertically oriented atherectomized tissues and the correlation between them with intravascular ultrasound image. In addition, this new method might be applied to various tissues in different ways.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94936
DOI
10.1016/j.prp.2011.06.007
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
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Link
 http://www.sciencedirect.com/science/article/pii/S0344033811001464
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