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Delayed high-quality CPR does not improve outcomes

Authors
 정성필 
Citation
 Resuscitation, Vol.82(Suppl. 2) : S52~S55, 2011 
Journal Title
 Resuscitation 
ISSN
 0300-9572 
Issue Date
2011
Abstract
AIM OF STUDY: The quality of cardiopulmonary resuscitation (CPR) is an important factor in the outcome of cardiac arrest. Our objective was to compare outcomes following either immediate low-quality (LQ) CPR or delayed high-quality (HQ) CPR. We hypothesized that delayed HQ CPR will improve the outcomes of CPR in comparison to immediately performing LQ CPR. METHODS: Eighteen Sprague-Dawley rats were randomized into two groups: (1) Delayed HQ CPR (HQ group, n = 9). (2) Immediate LQ CPR (LQ group, n = 9). Ventricular fibrillation (VF) was induced and untreated for 8 mins. CPR was immediately performed in LQ group for 5 mins. Compression depth was set at 70% of the "optimal compression depth". VF was untreated for an additional 5 mins in HQ group. HQ CPR was started together with ventilation (100% oxygen) and external hypothermia for 8 mins in both groups. The "optimal compression depth" was approximately 30% of the anteroposterior chest diameter. Epinephrine was administrated 3 mins prior to defibrillation attempt. Restoration of spontaneous circulation, postresuscitation myocardial function and survival time were monitored. RESULTS: All animals in the LQ group and 7 of 9 animals in the HQ group were resuscitated. Myocardial function, including ejection fraction and cardiac output was better in the LQ group than in the HQ group (p < 0.05) and survival time was longer in the LQ group (p < 0.05). CONCLUSION: The outcomes after immediate LQ CPR, were better than those after delayed HQ CPR in this rat model of cardiac arrest and resuscitation.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94868
DOI
10.1016/S0300-9572(11)70152-6
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Emergency Medicine
Yonsei Authors
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Link
 http://www.sciencedirect.com/science/article/pii/S0300957211701526
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