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분만 방법이 소아 알레르기질환의 유병률에 미치는 영향

Authors
 이용주 ; 지혜미 ; 김경원 ; 홍수종 ; 김규언 ; 손명현 ; 김우경 ; 이소연 ; 유진호 ; 김효빈 ; 김병주 
Citation
 Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지), Vol.21(3) : 197~206, 2011 
Journal Title
 Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지) 
ISSN
 1225-679x 
Issue Date
2011
Abstract
PURPOSE: It has been suggested that caesarean section is a risk factor for allergic diseases under the 'hygiene hypothesis', but it remains controversial. In this study, we examined the association between mode of delivery and development of allergic diseases. METHODS: The Korean International Study of Asthma and Allergies in Childhood questionnaire was used to survey 8,404 elementary and middle-school students in Seoul between April and October 2008. We categorized children into a caesarean section group and a vaginal delivery group, and surveyed the prevalence of asthma, allergic rhinitis, and atopic dermatitis. RESULTS: No differences in the prevalence of "wheeze ever" (P=0.418), "wheezing the last 12 months" (P=0.152), and "diagnosis of asthma ever" (P=0.382) were observed between the caesarean section group and the vaginal delivery group. The prevalence of "rhinitis ever" (P=0.609), "rhinitis the last 12 months" (P=0.788), and "diagnosis of allergic rhinitis ever" (P=0.700) was also similar between the two groups. The prevalence of "itchy eczema ever" (P=0.065), "itchy eczema last 12 months" (P=0.381), and a "diagnosis of atopic dermatitis ever" (P=0.162) also did not show any differences between the two groups. However, in subjects with a family history of allergic disease, the caesarean section group had the higher prevalence of "diagnosis of asthma ever" (11.3% vs. 9.2%, P=0.032) than that in the vaginal delivery group. CONCLUSION: We found an association between mode of delivery and the subsequent development of asthma in children with a family history of allergic disease in Seoul, Korea.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94710
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1. 연구논문 > 1. College of Medicine > Dept. of Pediatrics
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